When nutrition interacts with osteoblast function: molecular mechanisms of polyphenols

A Trzeciakiewicz, V Habauzit… - Nutrition Research …, 2009 - cambridge.org
Recent research has provided insights into dietary components that may optimise bone
health and stimulate bone formation. Fruit and vegetable intake, as well as grains and other …

Habitual flavonoid intakes are positively associated with bone mineral density in women

A Welch, A MacGregor, A Jennings… - Journal of Bone and …, 2012 - academic.oup.com
Dietary flavonoids exert bone‐protective effects in animal models, but there is limited
information on the effect of different flavonoid subclasses on bone health in humans. The …

A mechanistic review of chinese medicine polyphenols on bone formation and resorption

Y Li, L Li, X Li, B Luo, Q Ye, H Wang, L Yang… - Frontiers in …, 2022 - frontiersin.org
Bone reconstruction includes a steady state system of bone formation and bone absorption.
This tight coupling requires subtle coordination between osteoblasts and osteoclasts. If this …

Bioactivity, Molecular Mechanism, and Targeted Delivery of Flavonoids for Bone Loss

AR Sharma, YH Lee, A Bat-Ulzii, S Chatterjee… - Nutrients, 2023 - mdpi.com
Skeletal disabilities are a prominent burden on the present population with an increasing life
span. Advances in osteopathy have provided various medical support for bone-related …

Association between dietary intake of flavonoid and bone mineral density in middle aged and elderly Chinese women and men

ZQ Zhang, LP He, YH Liu, J Liu, YX Su… - Osteoporosis …, 2014 - Springer
This large cross-sectional study examined the associations of dietary intakes of total
flavonoids and their subtypes with bone density in women and men. We found that greater …

Terpenoid treatment in osteoporosis: this is where we have come in research

D Bellavia, F Caradonna, E Dimarco, V Costa… - Trends in Endocrinology …, 2021 - cell.com
Lower bone resistance to load is due to the imbalance of bone homeostasis, where
excessive bone resorption, compared with bone formation, determines a progressive …

[HTML][HTML] Antioxidant, anti-inflammatory, anti-diabetic, and pro-osteogenic activities of polyphenols for the treatment of two different chronic diseases: type 2 diabetes …

ES Scarpa, A Antonelli, G Balercia, S Sabatelli… - Biomolecules, 2024 - mdpi.com
Polyphenols are natural bioactives occurring in medicinal and aromatic plants and food and
beverages of plant origin. Compared with conventional therapies, plant-derived …

Epigenetic regulation of bone remodeling by natural compounds

N Raut, SM Wicks, TO Lawal, GB Mahady - Pharmacological research, 2019 - Elsevier
Osteoporosis and osteopenia impact more than 54 million Americans, resulting in significant
morbidity and mortality. Alterations in bone remodeling are the hallmarks for osteoporosis …

Genistein aglycone: a dual mode of action anti-osteoporotic soy isoflavone rebalancing bone turnover towards bone formation

A Bitto, F Polito, F Squadrito, H Marini… - Current Medicinal …, 2010 - ingentaconnect.com
Osteoporosis is characterized by reduced bone mass and structural deterioration of bone
tissue leading to enhanced bone fragility and a consequent increase in fracture risk. Bone …

Effects of Isoflavonoid and Vitamin D Synergism on Bone Mineral Density—A Systematic and Critical Review

M Miedziaszczyk, A Maciejewski, I Idasiak-Piechocka… - Nutrients, 2023 - mdpi.com
Phytoestrogens are non-steroidal plant compounds, which bind to α and β estrogen
receptors, thereby causing specific effects. The best-known group of phytoestrogens are …