Introduction: Osteoporosis is a chronic, skeletal disorder characterized by compromised
bone strength and increased fracture risk; it affects 50% of women and 20% of men. In the …

Background and objective Dietary intake of fruits and vegetables has been suggested to
have a role in promoting bone health. More specifically, the polyphenols they contain have …

Estrogen deficiency is a major risk factor for osteoporosis in postmenopausal women.
Although hormone replacement therapy (HRT) has been rampantly used to recompense for …

Although safe and effective agents are currently available to treat osteoporosis, fragility
fractures remain a significant problem worldwide. Recent improvements in the …

Osteoporosis is a disease of bone characterized by loss of bone matrix and deterioration of
bone microstructure that leads to an increased risk of fracture. Cross-sectional studies have …

Aging and sex hormones related changes lead to inflammatory and oxidant conditions,
which are involved in the pathogenesis of osteoporosis. Recent studies have suggested that …

Background and aims. Bone remodeling in which old or damaged bone cells are removed
by osteoclasts, and new bone cells are developed by osteoblasts is a key target for …

Bone is a living, dynamic tissue that is continuously remodeled during the adult life of an
individual. A helpful concept is the notion that bone is remodeled in quantum units called …

Estrogen deficiency has been considered the seminal mechanism of osteoporosis in both
women and men, but epidemiological evidence in humans and recent mechanistic studies …

To summarize promising areas of investigation in osteoporosis and to stimulate further
research in this area, as discussed in a recent international conference. Over the recent …