Objective The goal of this narrative review is to provide an overview of migraine
pathophysiology, with an emphasis on the role of calcitonin gene‐related peptide (CGRP) …

Migraine treatment has reached a new era with the development of drugs that target the
trigeminal neuropeptide calcitonin gene-related peptide (CGRP) or its receptor. The CGRP …

Abstract Treatment of migraine is on the cusp of a new era with the development of drugs
that target the trigeminal sensory neuropeptide calcitonin gene-related peptide (CGRP) or its …

Migraine is a strongly disabling disease characterized by a unilateral throbbing headache
lasting for up to 72 h for each individual attack. There have been many theories on the …

Background Migraine is a disabling and chronic neurovascular headache disorder.
Trigeminal vascular activation and release of calcitonin gene-related peptide (CGRP) play a …

Premise The brain and the sensory nervous system contain a rich supply of calcitonin gene-
related peptide (CGRP) and CGRP receptor components. Clinical studies have …

The neuropeptide calcitonin gene‐related peptide (CGRP) is implicated in the underlying
pathology of migraine. Serum levels of CGRP, which are elevated during a migraine attack …

Migraine is a common neurological disorder that afflicts up to 15% of the adult population in
most countries, with predominance in females. It is characterized by episodic, often disabling …

Over the past 300 years, the migraine field has been dominated by two main theories—the
vascular theory and the central neuronal theory. The success of vasoconstrictors such as …

Migraine is one of the most prevalent and disabling neurovascular disorders worldwide.
However, despite the increase in awareness and research, the understanding of migraine …