The 'neuroadrenergic hypothesis' in hypertension: current evidence

G Grassi, G Seravalle… - Experimental …, 2010 - Wiley Online Library
Data collected in experimental animals and in humans support the hypothesis that
sympathetic neural mechanisms are involved in the development and progression of …

Essential hypertension and the sympathetic nervous system

G Grassi, F Quarti-Trevano, R Dell'Oro, G Mancia - Neurological sciences, 2008 - Springer
Sympathetic neural factors exert a key role in homeostatic blood pressure control. Evidence
is available that abnormalities in sympathetic function may favour the development and …

Sympathetic neural activity in hypertension and related diseases

G Grassi - American journal of hypertension, 2010 - academic.oup.com
Background Several hemodynamic variables, such as blood pressure, vascular resistance,
cardiac output, and heart rate, are regulated, among others, by sympathetic cardiovascular …

Assessment of sympathetic cardiovascular drive in human hypertension: achievements and perspectives

G Grassi - Hypertension, 2009 - Am Heart Assoc
Methodological refinements in the assessment of human sympathetic cardiovascular drive
have allowed throughout the years to better define the role of the sympathetic nervous …

Evidence for a critical role of the sympathetic nervous system in hypertension

G Grassi, VS Ram - Journal of the American Society of Hypertension, 2016 - Elsevier
Autonomic cardiovascular control is impaired in hypertension, leading to a reduction in the
parasympathetic tone and to an increase in the sympathetic influences to the heart and …

Björn Folkow Award Lecture The sympathetic nervous system in hypertension

G Mancia - Journal of hypertension, 1997 - journals.lww.com
There is clear evidence that essential hypertension is accompanied by sympathetic
activation. Many studies have shown that a number of cardiovascular risk factors frequently …

The autonomic nervous system and hypertension

G Mancia, G Grassi - Circulation research, 2014 - Am Heart Assoc
Physiological studies have long documented the key role played by the autonomic nervous
system in modulating cardiovascular functions and in controlling blood pressure values …

Sympathetic activity, blood pressure variability and end organ damage in hypertension.

G Mancia, MD Rienzo, G Parati… - Journal of human …, 1997 - search.ebscohost.com
Animal studies have provided clearcut evidence that sympathetic factors are involved in the
development and maintenance of high blood pressure (BP). This also appears to be the …

Sympathetic activation in the pathogenesis of hypertension and progression of organ damage

G Mancia, G Grassi, C Giannattasio, G Seravalle - Hypertension, 1999 - Am Heart Assoc
Although animal models of hypertension have clearly shown that high blood pressure is
associated with and is probably caused by an increase in sympathetic cardiovascular …

Sympathetic nervous system and hypertension: New evidences

G Seravalle, G Grassi - Autonomic Neuroscience, 2022 - Elsevier
Evidences collected in the past few years have strengthened the concept that the
sympathetic nervous system plays a primary role in the development and progression of the …