Silencing phospholipid scramblase 1 expression by RNA interference in colorectal cancer and metastatic liver cancer
W Cui, SY Li, JF Du, ZM Zhu, P An - Hepatobiliary & pancreatic diseases …, 2012 - Elsevier
Background Phospholipid scramblase 1 (PLSCR1) not only participates in the transbilayer
movement of phospholipids, but also plays a role in the pathogenesis and progression of …
movement of phospholipids, but also plays a role in the pathogenesis and progression of …
[HTML][HTML] RNA interference‑mediated downregulation of phospholipid scramblase 1 expression in primary liver cancer in vitro
L Gui, YW Zhu, Q Xu, JJ Huang, P Hua… - Oncology …, 2020 - spandidos-publications.com
Abstract Phospholipid scramblase 1 (PLSCR1) serves a function in the pathogenesis and
progression of various types of cancer. However, the role of PLSCR1 in human primary liver …
progression of various types of cancer. However, the role of PLSCR1 in human primary liver …
[HTML][HTML] Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo
CW Fan, CY Chen, KT Chen, CR Shen, YB Kuo… - Journal of translational …, 2012 - Springer
Background Membrane-bound phospholipid scramblase 1 (PLSCR1) is involved in both
lipid trafficking and cell signaling. Previously, we showed that PLSCR1 is overexpressed in …
lipid trafficking and cell signaling. Previously, we showed that PLSCR1 is overexpressed in …
[HTML][HTML] Identification of phospholipid scramblase 1 as a biomarker and determination of its prognostic value for colorectal cancer
YB Kuo, CC Chan, CA Chang, CW Fan, RP Hung… - Molecular …, 2011 - Springer
The purpose of this study was to examine the expression of phospholipid scramblase 1
(PLSCR1) in tumor tissues and plasma specimens of patients with colorectal cancer (CRC) …
(PLSCR1) in tumor tissues and plasma specimens of patients with colorectal cancer (CRC) …
Phospholipid scramblase 1.
Y Huang, Q Zhao, GQ Chen - Sheng li xue bao:[Acta Physiologica …, 2006 - europepmc.org
Phospholipid scramblase 1 (PLSCR1) is a calcium-binding, multiply palmitoylated type II
endofacial plasma membrane protein, while unpalmitoylated PLSCR1 protein can import …
endofacial plasma membrane protein, while unpalmitoylated PLSCR1 protein can import …
Snail interacts with hPLSCR1 promoter and down regulates its expression in IMR-32
VG Francis, P Padmanabhan, SN Gummadi - Biochemical and Biophysical …, 2014 - Elsevier
Abstract Human phospholipid scramblase 1 (hPLSCR1) is a proapoptotic protein whose
expression is deregulated in a variety of cancers cells. However till date the transcription …
expression is deregulated in a variety of cancers cells. However till date the transcription …
Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells
Y Huang, Q Zhao, CX Zhou, ZM Gu, D Li, HZ Xu… - Oncogene, 2006 - nature.com
Abstract Phospholipid scramblase 1 (PLSCR1) is a multiply palmitoylated protein which is
localized in either the cell membrane or nucleus depending on its palmitoylated state. The …
localized in either the cell membrane or nucleus depending on its palmitoylated state. The …
Two c-Myc binding sites are crucial in upregulating the expression of human phospholipid scramblase 1 gene
JM Vinnakota, SN Gummadi - Biochemical and biophysical research …, 2016 - Elsevier
Abstract Human phospholipid scramblase 1 (hPLSCR1) is a type II endofacial membrane
protein which mediates bi-directional transport of phospholipids across the plasma …
protein which mediates bi-directional transport of phospholipids across the plasma …
[HTML][HTML] Identification and characterization of the novel nuclease activity of human phospholipid scramblase 1
Background Human phospholipid scramblase 1 (hPLSCR1) was initially identified as a Ca
2+ dependent phospholipid translocator involved in disrupting membrane asymmetry …
2+ dependent phospholipid translocator involved in disrupting membrane asymmetry …
[HTML][HTML] Phospholipid Scramblase 1, an interferon-regulated gene located at 3q23, is regulated by SnoN/SkiL in ovarian cancer cells
Background Treatment of advanced stage ovarian cancer continues to be challenging due
to acquired drug resistance and lack of early stage biomarkers. Genes identified to be …
to acquired drug resistance and lack of early stage biomarkers. Genes identified to be …
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