Placental lipid metabolism is likely to be a determinant of placental transfer of fatty acids to
the fetus. Maternal conditions, such as obesity, have now been shown to regulate placental …

The factors determining fatty acid transfer across the placenta are not fully understood. This
study used a combined experimental and computational modeling approach to explore …

Both in-vitro and human in-vivo studies using labeled fatty acids (FAs) reported a
preferential placental–fetal transfer of long-chain polyunsaturated fatty acids, although the …

Background: The increasing incidence of childhood obesity is a significant public health
challenge, the consequences of which extend across the life course. Summary: Diet and …

The prevalence of adult and childhood obesity are increasing. Most of the human newborn's
body fat accumulates in the last half of intrauterine life. Fat in the fetus was thought to be …

The human foetus depends on placental transfer for the fatty acids required for its growth
and development. Long chain polyunsaturated fatty acids (LC-PUFAs) may specifically …

During pregnancy, maternal plasma fatty acids are critically required for cell growth and
development, cell signaling, and the development of critical structural and functional aspects …

More than 90 per cent of the fat deposition in the fetus occurs in the last 10 weeks of
pregnancy during which it increases exponentially to reach a rate of accretion of around …

Abstract Knowledge of the consequences of maternal obesity in human placental fatty acids
(FA) transport and metabolism is limited. Animal studies suggest that placental uptake of …

The functionality of the placenta may affect neonatal adiposity and fetal levels of key
nutrients such as long-chain polyunsaturated fatty acids. Fetal macrosomia and its …