Background Current estimates from objective accelerometer data suggest that American
adults are sedentary for∼ 7.7 h/day. Historically, sedentary behaviour was conceptualized …

Background Epidemiological studies assessing the association between sedentary time and
cardiovascular diseases (CVD) risks have been published at a rapid pace in recent years …

Epidemiological evidence is accumulating that indicates greater time spent in sedentary
behavior is associated with all-cause and cardiovascular morbidity and mortality in adults …

Cardiovascular disease (CVD) is highly prevalent and can lead to disability and premature
mortality. Sedentary behaviour, defined as a low energy expenditure while sitting or lying …

The majority of adults do not meet current guideline recommendations for moderate to
vigorous physical activity. Recent research has linked a high amount of sedentary behavior …

Importance Prior studies suggest that higher sedentary time is associated with a greater risk
for cardiovascular disease (CVD). However, the quantitative, dose-response association …

Sedentary behavior, as distinct from a lack of moderate-to-vigorous physical activity, is an
emerging health risk behavior for the development of chronic diseases. Examples of …

Purpose To determine the dose-response associations of sedentary behaviour with
cardiovascular diseases (CVD), cancer, and all-cause mortality, and to examine whether the …

Background The appropriate limit to the amount of daily sedentary time (ST) required to
minimize mortality is uncertain. This meta-analysis aimed to quantify the dose-response …

Background Sedentary behaviour has been proposed to be detrimentally associated with
cardio-metabolic risk independently of moderate to vigorous physical activity (MVPA) …