Carcinogen risk assessment in the US Environmental Protection Agency
RE Albert - Critical reviews in toxicology, 1994 - Taylor & Francis
This is a narrative account of the origins and development of carcinogen risk assessment in
the US EPA, which pioneered the field. It began in an era of high hopes that the regulation of …
the US EPA, which pioneered the field. It began in an era of high hopes that the regulation of …
US Environmental Protection Agency guidelines for carcinogen risk assessment: past and future
J Wiltse, VL Dellarco - Mutation Research/Reviews in Genetic Toxicology, 1996 - Elsevier
The US Environmental Protection Agency (USEPA) recently proposed new guidelines to
update and replace the 1986 USEPA Guidelines for Carcinogen Risk Assessment. Today …
update and replace the 1986 USEPA Guidelines for Carcinogen Risk Assessment. Today …
Rationale developed by the Environmental Protection Agency for the assessment of carcinogenic risks
RE Albert, RE Train, E Anderson - Journal of the National …, 1977 - academic.oup.com
The intent of the Environmental Protection Agency's “Interim Guideline for Carcinogen Risk
Assessment” is to provide an evaluation of the evidence regarding suspect carcinogens that …
Assessment” is to provide an evaluation of the evidence regarding suspect carcinogens that …
International cancer risk assessment: the impact of biologic mechanisms
J Whysner, GM Williams - Regulatory Toxicology and Pharmacology, 1992 - Elsevier
The use of risk assessment by different governments and agencies varies widely in theory
and practice. One major difference is in the consideration given to the biologic mechanisms …
and practice. One major difference is in the consideration given to the biologic mechanisms …
US Environmental Protection Agency's revised guidelines for carcinogen risk assessment: incorporating mode of action data
VL Dellarco, JA Wiltse - Mutation Research/Fundamental and Molecular …, 1998 - Elsevier
The understanding of whether exposure to environmental agents potentially results in
human cancers has long been a key component of health risk assessment and regulatory …
human cancers has long been a key component of health risk assessment and regulatory …
Human carcinogenic risk evaluation, part IV: assessment of human risk of cancer from chemical exposure using a global weight-of-evidence approach
JS MacDonald - Toxicological Sciences, 2004 - academic.oup.com
In the early 1960s, the National Cancer Institute developed procedures to formalize the
process for the evaluation of the human risk of cancer from chemical exposure (Boorman …
process for the evaluation of the human risk of cancer from chemical exposure (Boorman …
Mechanisms of multistep carcinogenesis and carcinogen risk assessment.
JC Barrett - Environmental health perspectives, 1993 - ehp.niehs.nih.gov
Many different types of chemical exposures can increase the incidence of tumors in animals
and humans, but usually a long period of time is required before the carcinogenic risk of an …
and humans, but usually a long period of time is required before the carcinogenic risk of an …
The science and practice of carcinogen identification and evaluation
VJ Cogliano, RA Baan, K Straif, Y Grosse… - Environmental …, 2004 - ehp.niehs.nih.gov
Several national and international health agencies have established programs with the aim
of identifying agents and exposures that cause cancer in humans. Carcinogen identification …
of identifying agents and exposures that cause cancer in humans. Carcinogen identification …
Carcinogenic risk assessment: A guide to the literature
D Krewski, C Brown - Biometrics, 1981 - JSTOR
Carcinogenic Risk Assessment: A Guide to the Literature Page 1 B IOMETRICS 3 7, 3 5 3-3
6 6 June 1981 Carcinogenic Risk Assessment: A Guide to the Literature Daniel Krewski …
6 6 June 1981 Carcinogenic Risk Assessment: A Guide to the Literature Daniel Krewski …
Use of human data in quantitative risk assessment of carcinogens: impact on epidemiologic practice and the regulatory process
RE Shore, V Iyer, B Altshuler, BS Pasternack - Regulatory Toxicology and …, 1992 - Elsevier
Epidemiologic data are increasingly being used to assess cancer risk from chemicals as
their value is recognized and as more and better studies become available. Weight-of …
their value is recognized and as more and better studies become available. Weight-of …