The use of Chinese yang/qi-invigorating tonic botanical drugs/herbal formulations in ameliorating chronic kidney disease by enhancing mitochondrial function

J Tian, Y Huang, T Wu, HD Huang, KM Ko… - Frontiers in …, 2021 - frontiersin.org
Background: Chronic kidney disease (CKD) is a leading cause of morbidity and mortality.
Mitochondrial dysfunction has been implicated as a key factor in the development of CKD …

Mitochondrial targeting of herbal medicine in chronic kidney disease

Q Li, C Xing, Y Yuan - Frontiers in Pharmacology, 2021 - frontiersin.org
Chronic kidney disease (CKD) is a common progressive disease that is typically
characterized by the permanent loss of nephrons and an eventual decline in glomerular …

[HTML][HTML] Advances in the pharmacological study of Chinese herbal medicine to alleviate diabetic nephropathy by improving mitochondrial oxidative stress

M Chen, Y Chen, W Zhu, X Yan, J Xiao, P Zhang… - Biomedicine & …, 2023 - Elsevier
Diabetic nephropathy (DN) is one of the serious complications of diabetes mellitus, primarily
arising from type 2 diabetes (T2DM), and can progress to chronic kidney disease (CKD) and …

Protective effect of natural products in the metabolic-associated kidney diseases via regulating mitochondrial dysfunction

P Liu, Y Chen, J Xiao, W Zhu, X Yan… - Frontiers in …, 2023 - frontiersin.org
Metabolic syndrome (MS) is a complex group of metabolic disorders syndrome with
hypertension, hyperuricemia and disorders of glucose or lipid metabolism. As an important …

Huangqi‐Danshen decoction ameliorates adenine‐induced chronic kidney disease by modulating mitochondrial dynamics

X Liu, S Huang, F Wang, L Zheng, J Lu… - Evidence‐Based …, 2019 - Wiley Online Library
Chronic kidney disease (CKD) is a leading public health problem with high morbidity and
mortality. However, the therapies remain limited. Traditional Chinese medicine (TCM) has …

Jian-Pi-Yi-Shen Formula ameliorates chronic kidney disease: involvement of mitochondrial quality control network

X Liu, J Chen, X Liu, D Wang, P Zheng, A Qi… - … and Alternative Medicine, 2018 - Springer
Abstract Background Jian-Pi-Yi-Shen Formula (JPYSF), a Chinese herbal decoction with the
efficacies of 'fortify the spleen and tonify the kidney'and 'activate blood and resolve stasis', is …

Renoprotective potentials of small molecule natural products targeting mitochondrial dysfunction

MA Rahman, S Akter, D Dorotea… - Frontiers in …, 2022 - frontiersin.org
Kidney diseases, including acute kidney injury (AKI) and chronic kidney disease (CKD),
have become critical clinical, socioeconomic, and public health concerns worldwide. The …

Jian‐Pi‐Yi‐Shen Formula Alleviates Chronic Kidney Disease in Two Rat Models by Modulating QPRT/NAD+/SIRT3/Mitochondrial Dynamics Pathway

X Liu, S Liu, B Zhang, D Luo, S Huang… - Evidence‐Based …, 2021 - Wiley Online Library
Objective. Jian‐Pi‐Yi‐Shen formula (JPYSF) is a traditional Chinese herbal decoction and
has been used for treating chronic kidney disease (CKD) in clinics for decades. However …

[HTML][HTML] Natural products for kidney disease treatment: Focus on targeting mitochondrial dysfunction

J Huang, Y Liang, L Zhou - Frontiers in Pharmacology, 2023 - frontiersin.org
The patients with kidney diseases are increasing rapidly all over the world. With the rich
abundance of mitochondria, kidney is an organ with a high consumption of energy. Hence …

New Insights into the Chemical and Biochemical Basis of the “Yang‐Invigorating” Action of Chinese Yang‐Tonic Herbs

J Chen, HS Wong, PK Leong, HY Leung… - Evidence‐Based …, 2014 - Wiley Online Library
In the practice of traditional Chinese medicine, many Yang‐tonic herbs have been used for
retarding the decline in bodily function and delaying the onset of age‐related diseases. Our …