A case for evolutionary genomics and the comprehensive examination of sequence biodiversity

DD Pollock, JA Eisen, NA Doggett… - Molecular Biology and …, 2000 - academic.oup.com
Comparative analysis is one of the most powerful methods available for understanding the
diverse and complex systems found in biology, but it is often limited by a lack of …

[图书][B] Handbook of comparative genomics: principles and methodology

C Saccone, G Pesole - 2003 - books.google.com
This comprehensive reference covers the comparative methodology involved in studying
molecular evolution. Providing a practical introduction to the role of bioinformatics in …

[HTML][HTML] Roadmap to the study of gene and protein phylogeny and evolution—A practical guide

F Jacques, P Bolivar, K Pietras, EU Hammarlund - Plos one, 2023 - journals.plos.org
Developments in sequencing technologies and the sequencing of an ever-increasing
number of genomes have revolutionised studies of biodiversity and organismal evolution …

Genome-tools: a flexible package for genome sequence analysis

W Lee, SL Chen - Biotechniques, 2024 - Taylor & Francis
Genome-tools is a Perl module, a set of programs, and a user interface that facilitates access
to genome sequence information. The package is flexible, extensible, and designed to be …

Comparative genomics

NH Bergman - 2007 - books.google.com
This volume provides a collection of robust protocols for molecular biologists studying
comparative genomics. Each chapter includes detailed instructions for using a particular tool …

Genomicus: a database and a browser to study gene synteny in modern and ancestral genomes

M Muffato, A Louis, CE Poisnel, HR Crollius - Bioinformatics, 2010 - academic.oup.com
Comparative genomics remains a pivotal strategy to study the evolution of gene
organization, and this primacy is reinforced by the growing number of full genome …

Comparative genomics as a tool to understand evolution and disease

J Alföldi, K Lindblad-Toh - Genome research, 2013 - genome.cshlp.org
When the human genome project started, the major challenge was how to sequence a 3
billion letter code in an organized and cost-effective manner. When completed, the project …

Detecting highly conserved regions of the human genome by multispecies sequence comparisons

EH Margulies, ED Green… - Cold Spring Harbor …, 2003 - symposium.cshlp.org
The insights gained from subsequent comparisons of the resulting data have catalyzed
numerous additional genome-sequencing projects, with the largest efforts focusing on the …

Genomicus: five genome browsers for comparative genomics in eukaryota

A Louis, M Muffato, H Roest Crollius - Nucleic acids research, 2012 - academic.oup.com
Abstract Genomicus (http://www. dyogen. ens. fr/genomicus/) is a database and an online
tool that allows easy comparative genomic visualization in> 150 eukaryote genomes. It …

Phylogenetic analysis and comparative genomics

JA Lake, JE Moore - Trends in Biotechnology, 1998 - cell.com
Molecular sequence analysis is an evolving field important to phylogenetic analysis and
comparative genomics. Here, some of the pitfalls and practical solutions in this young but …