Protective effects of total flavonoids from Clinopodium chinense (Benth.) O. Ktze on myocardial injury in vivo and in vitro via regulation of Akt/Nrf2/HO-1 pathway

HJ Zhang, RC Chen, GB Sun, LP Yang, XD Xu, XB Sun - Phytomedicine, 2018 - Elsevier
Abstract Background Clinopodium chinense (Benth.) O. Ktze is a traditional Chinese herbal
medicine, which comprises the plant's total flavonoids. TFCC plays an important role in the …

Total Flavonoids from Clinopodium chinense (Benth.) O. Ktze Protect against Doxorubicin‐Induced Cardiotoxicity In Vitro and In Vivo

RC Chen, XD Xu, X Zhi Liu, GB Sun… - Evidence‐Based …, 2015 - Wiley Online Library
Doxorubicin has cardiotoxic effects that limit its clinical benefit in cancer patients. This study
aims to investigate the protective effects of the total flavonoids from Clinopodium chinense …

Tournefolic acid B, derived from Clinopodium chinense (Benth.) Kuntze, protects against myocardial ischemia/reperfusion injury by inhibiting endoplasmic reticulum …

Y Yu, N Xing, X Xu, Y Zhu, S Wang, G Sun, X Sun - Phytomedicine, 2019 - Elsevier
Background Protection the heart from ischemia/reperfusion (I/R) injury is an area of intense
research, as myocardial infarction is a major cause of mortality and morbidity all around the …

Total flavonoids from Anchusa italica Retz. Improve cardiac function and attenuate cardiac remodeling post myocardial infarction in mice

S Wang, Y Zhao, J Song, R Wang, L Gao… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance The plant Anchusa italica Retz.(Anchusa azurea
Mill.) has been traditionally used in Uygur medicine for the treatment of cardiovascular and …

Apigenin-7-O-β-d-(6″-p-coumaroyl)-glucopyranoside reduces myocardial ischaemia/reperfusion injury in an experimental model via regulating the inflammation …

W Quan, S Ma, Y Zhu, Q Shao, J Hou… - Pharmaceutical biology, 2020 - Taylor & Francis
Abstract Context Traditionally, Clematis tangutica Korsh.(Ranunculaceae) is used as a
Tibetan herb for treating indigestion and blood stasis in China. Recently, a flavonoid …

The cardioprotective effect of total flavonoids on myocardial ischemia/reperfusion in rats

D Lv, X Cheng, L Tang, M Jiang - Biomedicine & Pharmacotherapy, 2017 - Elsevier
The flowers of Abelmoschus manihot (L.) Medic is a traditional Chinese medicine used for
the treatment of ischemic diseases. The present study is to investigate whether total flavones …

Antioxidative and Cardioprotective Effects of Total Flavonoids Extracted from Dracocephalum moldavica L. Against Acute Ischemia/Reperfusion-Induced Myocardial …

J Jiang, X Yuan, T Wang, H Chen, H Zhao, X Yan… - Cardiovascular …, 2014 - Springer
This study evaluates antioxidative and cardioprotective effects of total flavonoids extracted
from Dracocephalum moldavica L.(DML). The total flavonoids showed remarkable …

Protective effects and chemical composition of Corchorus olitorius leaf fractions against isoproterenol-induced myocardial injury through p65NFkB-dependent anti …

B Alabi, T Omobowale, J Badejo… - Journal of Basic and …, 2020 - degruyter.com
Abstract Background The fractions of Corchorus olitorius leaf (COLF) were evaluated
against oxidative stress, inflammation and apoptosis in isoproterenol (ISO)-induced …

Cardioprotective activity of Cladosiphon okamuranus fucoidan against isoproterenol induced myocardial infarction in rats

P Thomes, M Rajendran, B Pasanban, R Rengasamy - Phytomedicine, 2010 - Elsevier
Fucoidans, sulfated polysaccharides of brown algae, have attracted steady attention in the
last few years as readily accessible biopolymers possessing a wide spectrum of biological …

[HTML][HTML] A new flavonoid glycoside (APG) isolated from Clematis tangutica attenuates myocardial ischemia/reperfusion injury via activating PKCε signaling

Y Zhu, S Di, W Hu, Y Feng, Q Zhou, B Gong… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Clematis tangutica has been shown to be beneficial for the heart; however, the mechanism
of this effectremains unknown. Apigenin-7-O-β-D-(-6 ″-p-coumaroyl)-glucopyranoside …