[PDF][PDF] A REVIEW ON INDOLO [2, 3-a] QUINOLIZIDINE: THE SYNTHETIC APPROACHES TO THE DEVELOPMENT OF BIOACTIVE INDOLO [2, 3-a] QUINOLIZIDINE …

S Sharma, Y Monga, A Gupta, S Singh - Heterocycles, 2023 - researchgate.net
Tetracyclic indolo [2, 3-a] quinolizidine motifs are an important class of molecules in
research and development due to their wide spectrum of biological activities, which include …

Indolo [3, 2-b] quinolines: synthesis, biological evaluation and structure activity-relationships

EVK Suresh Kumar, JR Etukala… - Mini reviews in …, 2008 - ingentaconnect.com
The tetracyclic indolo [3, 2-b] quinoline ring system constitutes an important structural moiety
in natural products exhibiting numerous biological activities. In particular, indolo [3, 2-b] …

Indolo [2, 3-a] quinolizidines and derivatives: bioactivity and asymmetric synthesis

M Perez, M Espadinha… - Current Pharmaceutical …, 2015 - ingentaconnect.com
Corynantheine alkaloids with a tetracyclic indole [2, 3-a]-quinolizidine motif are an important
issue in academia and in the life science industries due to their broad bioactivity profile. In …

6H-Indolo [2, 3-b] Quinoline: A Recent Synthetic Comprehension

HK Kadam, SG Tilve - Mini-Reviews in Organic Chemistry, 2019 - ingentaconnect.com
The present review provides a comprehensive overview of the synthetic methods developed
recently for 6H-Indolo [2, 3-b] quinoline. The review is classified into the following: 1) …

Quinolines, a perpetual, multipurpose scaffold in medicinal chemistry

P Yadav, K Shah - Bioorganic Chemistry, 2021 - Elsevier
Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …

[HTML][HTML] Stereoselective synthesis of a natural product inspired tetrahydroindolo [2, 3-a]-quinolizine compound library

MG Sankar, L Mantilli, J Bull, F Giordanetto… - Bioorganic & Medicinal …, 2015 - Elsevier
A natural product-inspired synthesis of a compound collection embodying the
tetrahydroindolo [2, 3-a] quinolizine scaffold was established with a five step synthesis route …

Highly stereoselective synthesis of the indolo [2, 3-a] quinolizine ring system and application to indole natural product synthesis

SM Allin, CI Thomas, JE Allard, K Doyle… - Tetrahedron letters, 2004 - Elsevier
We report a novel, facile and highly stereoselective approach to the indolo [2, 3-a]
quinolizine ring system from a readily available, non-racemic chiral template. We …

[HTML][HTML] Quinoline heterocycles: synthesis and bioactivity

YBRD Rajesh - Heterocycles-Synthesis and Biological Activities, 2018 - intechopen.com
Among heterocyclic compounds, quinoline is a privileged scaffold that appears as an
important construction motif for the development of new drugs. Quinoline nucleus is …

Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue

I Khan, A Ibrar, W Ahmed, A Saeed - European journal of medicinal …, 2015 - Elsevier
The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

Recent advances towards the synthesis of 4H-quinolizin-4-one

MR Kulkarni, ND Gaikwad - Tetrahedron, 2020 - Elsevier
Abstract 4H-quinolizin-4-one's is an important heterocyclic compound due to its wide range
of applications in medicinal chemistry and material science. Despite of the attractive …