This study evaluated whether a synergy exists for the combined treatment with lycopene and
synbiotic on early biomarkers of colon carcinogenesis. Male Wistar rats received a diet …

Chemoprevention of colorectal cancer has become essential in the modern industrialized
world as cancer of the large bowel has become one of the major causes of cancer mortality …

The inexorable increase in the incidence of colorectal cancer has led to growing interest in
its prevention by natural interventions. Thus, the present study was designed with the aim of …

Diet makes an important contribution to colorectal cancer (CRC) risk implying risks for CRC
are potentially reducible. Therefore, the probiotics have been suggested as the prophylactic …

Effects of proanthocyanidin (PA), procyanidin B-2 (B-2), and epigallocatechin gallate
(EGCG) on azoxymethane (AOM)-induced colonic preneoplastic aberrant crypt foci (ACF) …

Epidemiological and experimental observations have shown that nonsteroidal anti-
inflammatory drugs especially selective cyclooxygenase-2 (COX-2) inhibitors and probiotics …

Epidemiological evidence suggests that a diet abundant in fruits and vegetables may protect
against colon cancer. Bioactive compounds, including flavonoids and limonoids, have been …

A previous study indicated that lycopene could significantly inhibit the proliferation of human
colon cancer cells in vitro. However, the in vivo anticancer effects of lycopene against colon …

To evaluate the effect of a probiotic on the aggressiveness of a chemically induced
colorectal tumor in rats. Twenty-five male Fisher 344 rats, 250 g, provided with feed and …

On the basis of preliminary in vitro experience, we assessed whether an enriched nutritional
formulation with estrogen receptor (ER)-beta agonist and anti-inflammatory properties may …