The Active Metabolite of Vitamin D3 as a Potential Immunomodulator

I Szymczak, R Pawliczak - Scandinavian journal of immunology, 2016 - Wiley Online Library
In the past, vitamin D was known for its classical, skeletal action as a regulator of calcium
and bone homoeostasis. Currently, vitamin D was found to have a role in numerous …

Potential role of Vitamin D as an antiviral agent

J Ghosh - Medical Journal of Dr. DY Patil University, 2021 - journals.lww.com
Vitamin D has potential antimicrobial activity, the deficiency of which has deleterious effects
on the general well-being and longevity, predisposing major public health problem …

Translating the role of vitamin D3 in infectious diseases

AL Khoo, L Chai, H Koenen, I Joosten… - Critical reviews in …, 2012 - Taylor & Francis
Vitamin D3 affects both the innate as well as adaptive immune responses. Epidemiological
studies have established that vitamin D3 deficiency plays an important role in tuberculosis …

Crosstalk between vitamin D metabolism, VDR signalling, and innate immunity

R Lin - BioMed research international, 2016 - Wiley Online Library
The primary function of vitamin D is to regulate calcium homeostasis, which is essential for
bone formation and resorption. Although diet is a source of vitamin D, most foods are …

[PDF][PDF] The Effects of Vitamin D on Immune System and Inflammatory Diseases. Biomolecules 2021, 11, 1624

T Ao, J Kikuta, M Ishii - 2021 - eshop.treemed.cz
Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin
D receptor and 1↵-hydroxylase. In vitro studies have shown that 1, 25-dihydroxyvitamin D …

Vitamin D3 and the immune system: maintaining the balance in health and disease

F Baeke, E Van Etten, L Overbergh… - Nutrition research …, 2007 - cambridge.org
1, 25-Dihydroxyvitamin D3 (1, 25 (OH) 2D3), the active form of vitamin D3, is a central player
in Ca and bone metabolism. More recently, important immunomodulatory effects have been …

Vitamin D metabolism and signaling in the immune system

JH White - Reviews in endocrine and metabolic disorders, 2012 - Springer
Vitamin D has emerged as a pleiotropic regulator of human physiology, and recent work has
revealed that it has several roles in control of human immune system function. Vitamin D …

Vitamin D and infectious diseases

J Ghosn, JP Viard - Presse Medicale (Paris, France: 1983), 2013 - europepmc.org
Vitamin D plays a role in the synthesis of antibacterial peptids and in autophagy. Several
studies have shown that low levels of vitamin D are associated with the susceptibility and the …

Immunomodulatory properties of vitamin D in the intestinal and respiratory systems

FN Hamza, S Daher, HMA Fakhoury, WB Grant… - Nutrients, 2023 - mdpi.com
Vitamin D plays a crucial role in modulating the innate immune response by interacting with
its intracellular receptor, VDR. In this review, we address vitamin D/VDR signaling and how it …

Current perspectives on vitamin D, immune system, and chronic diseases

MC Borges, LA Martini, MM Rogero - Nutrition, 2011 - Elsevier
Accumulating data support that vitamin D possesses several biological and molecular
actions apart from its role in calcium homeostasis. Immune cells express vitamin D receptor …