Background Vitamin D has been suggested to influence the immune system, and vitamin D
metabolites and the vitamin D receptor (VDR) are generated and expressed in white blood …

Various kinds of immune cells-including dendritic cells, macrophages, T cells and B cells-
express the vitamin D receptor and 1α-hydroxylase (CYP27B1). In vitro studies have shown …

Vitamin D deficiency has been linked to an increased risk of a wide range of adverse health
outcomes. The active form of vitamin D has an important role in calcium metabolism and in …

Vitamin D was discovered as the cure for nutritional rickets. Classically, hormonal 1, 25-
dihydroxyvitamin D (1, 25D), produced in the kidney by CYP27B1-catalyzed 1α …

Vitamin D plays an active role beyond mineral metabolism and skeletal health, including
regulation of the immune system. Vitamin D deficiency is widely prevalent, and …

Historically, vitamin D is recognized as an essential component for the maintenance of the
musculoskeletal system. The immunomodulatory role of vitamin D in health and disease has …

Both adaptive and innate immune processes are two edged: beneficial and harmful.
Although suppression of adaptive immunity may be beneficial in a number of self-destructive …

Beyond its critical function in calcium homeostasis, vitamin D has recently been found to
play an important role in the modulation of the immune/inflammation system via regulating …

Vitamin D is involved in bone health by promoting calcium absorption in the gut and
maintaining serum calcium and phosphate concentrations, and by its action on bone growth …

Vitamin D, commonly known for its impact on bone metabolism, is vital in various bodily
processes, including regulating immune responses. The actions of vitamin D are carried out …