Vitamin D is widely reported to inhibit innate immune signalling and dendritic cell (DC)
maturation as a potential immunoregulatory mechanism. It is not known whether vitamin D …

Low vitamin D status is associated with an increased risk of Th1 mediated autoimmune
diseases like inflammatory bowel disease. 1, 25 (OH) 2D3 treatments have been shown to …

Vitamins and their metabolites are essential for many physiological processes including
immune response. In addition to regulating calcium homeostasis, vitamin D exerts various …

Ever since its discovery by Windhaus, the importance of the active metabolite of vitamin D (1,
25-dihydroxyvitamin D 3; 1, 25-(OH) 2D 3) has been ever expanding. In this review, the …

We investigated the mechanisms by which T-cell cytokines are able to influence the Toll-like
receptor (TLR)-induced, vitamin D-dependent antimicrobial pathway in human monocytes. T …

Vitamin D, in addition to its classical functions in bone homeostasis, has a modulatory and
regulatory role in multiple processes, including host defense, inflammation, immunity, and …

Studies over the last two decades have revealed profound immunomodulatory aspects of
vitamin D on various aspects of the immune system. This review will provide an overview of …

Abstract Purpose of Review To review the mechanisms by which vitamin D and its
metabolites regulate the immune system to facilitate the ability of the body to prevent and/or …

Vitamin D metabolites enhance immunity to a wide range of respiratory pathogens in vitro.
Numerous observational studies have investigated whether vitamin D deficiency is a risk …

Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …