Macroscale biomaterials, such as preformed implantable scaffolds and injectable soft
materials, possess powerful synergies with anti-cancer immunotherapies. Immunotherapies …

Although cancer immunotherapy is showing tremendous promise and has progressed to the
clinic, it has only achieved sporadic efficacy, with only a fraction of patients benefitting from …

Cancer immunotherapy, as a paradigm shift in cancer treatment, has recently received
tremendous attention. The active cancer vaccination, immune checkpoint blockage (ICB) …

Immunotherapy has attracted tremendous attention due to the remarkable clinical successes
for treating a broad spectrum of tumors. One challenge for cancer immunotherapy is the …

Cancer immunotherapy aims to leverage the immune system to suppress the growth of
tumors and to inhibit metastasis. The recent promising clinical outcomes associated with …

Highlights•Biomaterials can potentially improve the safety and efficacy of cancer
immunotherapy.•Biomaterials scaffolds can program immune cell function in peripheral …

The past decade has witnessed the accelerating development of immunotherapies for
cancer treatment. Immune checkpoint blockade therapies and chimeric antigen receptor …

Conspectus A major function of the immune system is to detect threat from foreign invaders,
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …

Immunotherapy is a promising treatment modality for cancer as it can promote specific and
durable anti-cancer responses. However, limitations to current approaches remain …

The past decade has witnessed the explosive development of cancer immunotherapies.
Nevertheless, low immunogenicity, limited specificity, poor delivery efficiency, and off‐target …