The skin is the front line of defense against insult and injury and contains many epidermal
and immune elements that comprise the skin-associated lymphoid tissue (SALT). The …

Psoriasis vulgaris is a multi-factorial heritable disease characterized by severe inflammation
resulting in poorly differentiated, hyperproliferative keratinocytes. Recent advances in …

Psoriasis is a complex inflammatory process resulting from activation of the well-defined
interleukin (IL)-23/T17 cytokine axis. We review the role of key cytokines IL-17 and IL-23 in …

Psoriasis vulgaris is the best-understood autoimmune skin disease mediated by the cells
and molecules of the innate and adaptive immune systems. In many ways, the immune …

Psoriasis is a complex chronic inflammatory skin disease caused by the dynamic interplay
between multiple genetic risk foci, environmental risk factors, and excessive immunological …

Psoriasis is a complex inflammatory disease mediated by tumor necrosis factor (TNF)-α and
cytokines secreted by specialized T-cell populations, eg, IL-17, IL-22, and IFN-γ. The …

Psoriasis is caused by a complex interplay between the immune system, psoriasis-
associated susceptibility loci, autoantigens, and multiple environmental factors. Over the last …

Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

Psoriasis is a chronic inflammatory skin disease with a clear genetic contribution,
characterized by keratinocyte proliferation and immune cell infiltration. Various closely …

Psoriasis is a common inflammatory skin disease with an incompletely understood etiology.
The disease is characterized by red, scaly and well-demarcated skin lesions formed by the …