Aim To compare the effects of oxysophoridine (Oxy) and sophoridine (Sop) on experimental
arrhythmias and myocardial physiologic properties. Methods Arrhythmias were induced by …

Background Sophoridine (SR) has shown the potential to be an antiarrhythmic agent.
However, SR's electrophysiological properties and druggability research are relatively …

Aim: To investigate the anti-arrhythmic effects of sulfamide analogues of changrolin and to
characterize the sulfate of compound 6f (sulcardine sulfate, Sul) as a novel anti-arrhythmic …

Aim: To examine the electrophysiological effects of sophocarpine on action potentials (AP)
and ionic currents of cardiac myocytes and to compare some of these effects with those of …

The effects of an ethanol extract of the plant Sophora flavescens Ait. on haemodynamics and
ventricular fibrillation threshold were studied in pentobarbitone-anesthetized dogs. It was …

The arrhythmias induced by chloroform-epinephine, BaCl2, and aconitine were prevented
and antagonized by Ophiopogon total saponins (OTS) which were extracted from the root of …

The effects of an ethanol extract of the plant Sophora flavescens Ait. on cardiac arrhythmias
induced by coronary artery ligation in rats, and by aconitine infusion in mice, were studied …

Oxymatrine is one of the main alkaloid components extracted from Sophora roots and has
been shown to play various protective roles in the cardiovascular system. The present study …

Aim To study the effects of osthole (Ost) on the isolated guinea pig atria and the relationship
between Ost effect and Ca2+. Methods Contractions of left atria were induced by electric …

Sophoridine is a type of alkaloid extract derived from the Chinese herb Sophora flavescens
Ait (kushen) and possess a variety of pharmacological effects including anti-inflammation …