T follicular‐like helper cells in the peripheral blood of patients with primary Sjögren's syndrome

KA Brokstad, M Fredriksen, F Zhou… - Scandinavian …, 2018 - Wiley Online Library
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease characterized by
exocrine gland dysfunction, mainly causing sicca symptoms. B cells have a prominent role in …

Follicular helper T cells and follicular regulatory T cells in the immunopathology of primary Sjögren's syndrome

W Chen, F Yang, G Xu, J Ma, J Lin - Journal of Leucocyte …, 2021 - academic.oup.com
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease, characterized by
lymphocytic infiltration into exocrine glands, which causes dry eyes, dry mouth, and systemic …

Association between T follicular helper cells and T peripheral helper cells with B-cell biomarkers and disease activity in primary Sjögren syndrome

A Dupré, J Pascaud, E Rivière, A Paoletti, B Ly… - RMD open, 2021 - rmdopen.bmj.com
INTRODUCTION Primary Sjögren syndrome (pSS) is a systemic autoimmune disease,
characterised by an infiltration of the exocrine glands, leading to sicca syndrome …

Follicular helper T cells may play an important role in the severity of primary Sjögren's syndrome

K Szabo, G Papp, S Barath, E Gyimesi, A Szanto… - Clinical …, 2013 - Elsevier
The aim of this study was to investigate the possible role of follicular helper T (TFH) cells in
the pathogenesis of primary Sjögren's syndrome (pSS) by analyzing immune-competent …

A comprehensive investigation on the distribution of circulating follicular T helper cells and B cell subsets in primary Sjögren's syndrome and systemic lupus …

K Szabó, G Papp, A Szántó, T Tarr… - Clinical & Experimental …, 2016 - academic.oup.com
Follicular T helper (Tfh) cells have a crucial role in regulating immune responses within
secondary lymphoid follicles by directing B cell differentiation towards memory B cells and …

The ratio of blood T follicular regulatory cells to T follicular helper cells marks ectopic lymphoid structure formation while activated follicular helper T cells indicate …

VR Fonseca, VC Romao, A Agua‐Doce… - Arthritis & …, 2018 - Wiley Online Library
Objective To investigate whether the balance of blood follicular helper T (Tfh) cells and T
follicular regulatory (Tfr) cells can provide information about ectopic lymphoid neogenesis …

[HTML][HTML] CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren's Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells

AC Hinrichs, AA Kruize, FPJG Lafeber… - International Journal of …, 2023 - mdpi.com
Primary Sjögren's syndrome (pSS) is an autoimmune disease characterised by B cell
hyperactivity. CXCR5+ follicular helper T cells (Tfh), CXCR5-PD-1hi peripheral helper T …

Circulating follicular helper–like T cells in systemic lupus erythematosus: association with disease activity

JY Choi, JH Ho, SG Pasoto, V Bunin… - Arthritis & …, 2015 - Wiley Online Library
Objective To assess circulating follicular helper T (Tfh)–like CD4+ T cells in patients with
systemic lupus erythematosus (SLE) and determine their relationship to disease activity …

[HTML][HTML] Circulating CCR7loPD-1hi follicular helper T cells indicate disease activity and glandular inflammation in patients with primary Sjögren's syndrome

JW Kim, J Lee, SM Hong, J Lee, ML Cho… - Immune …, 2019 - ncbi.nlm.nih.gov
Since primary Sjögren's syndrome (pSS) is an autoummune disease of B cell hyperactivity
and pathologic autoantibody response, follicular helper T (Tfh) cells and follicular regulatory …

Role of the frequency of blood CD4+ CXCR5+ CCR6+ T cells in autoimmunity in patients with Sjögren's syndrome

X Li, Z Wu, J Ding, Z Zheng, X Li, L Chen… - … and biophysical research …, 2012 - Elsevier
The blood CD4+ CXCR5+ T cells, known as “circulating” Tfh, have been shown to efficiently
induce naïve B cells to produce immunoglobulin. They play an important role in certain …