Immunoregulation represents a booming field of biomaterial design. The unique physical
and chemical properties of biomaterials offer tremendous opportunities for development …

Orthopaedic implants are highly susceptible to infection. The aims of treatment of infection
associated with internal fixation devices are fracture consolidation and prevention of chronic …

All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Device-associated infections (DAI) remain a serious concern in modern healthcare.
Bacterial attachment to a surface is the first step in biofilm formation, which is one of the main …

Implant related infections are the most common cause of joint arthroplasty failure, requiring
revision surgeries and a new implant, resulting in a cost of $8.6 billion annually. To address …

In implant infections, a quick and reliable identification of the etiological agent is crucial to
realizing efficacious therapies. Among molecular methods, automated ribotyping has proven …

Combination devices—those comprising drug releasing components together with
functional prosthetic implants—represent a versatile, emerging clinical technology promising …

Implantable devices have improved the lives of many patients, but implant-associated
infection remains a serious complication with significant morbidity and mortality. In recent …

The increasing clinical incidence and host risk of biomaterial‐centered infections, as well as
the reduced effectiveness of clinically relevant antibiotics to treat such infections, provide …

Infections related to implanted medical devices have become a significant health care issue
in recent decades. Increasing numbers of medical devices are in use, often in an aging …