We examined the role of dipeptidyl peptidase IV (DPP4) in the development of diabetes,
dyslipidaemia and renal dysfunction induced by streptozotocin (STZ). F344/DuCrlCrlj rats …

Background: It is poorly understood whether dipeptidyl peptidase 4 (DPP4) activity is altered
and how DPP4 contributes to glycemic control in patients with type 1 diabetes mellitus …

Background Dipeptidyl peptidase-4 (DPP-4) is an aminopeptidase that inhibits the
enzymatic degradation of glucagon-like peptide-1, glucose-dependent insulinotropic …

Dipeptidyl peptidase-4 (DPP-4), also known as the T-cell antigen CD26, is a multi-functional
protein which, besides its catalytic activity, also functions as a binding protein and a ligand …

Background Genetic polymorphisms of the Dipeptidyl Peptidase 4 (DPP4) gene may play a
role in the etiology of type 2 diabetes mellitus (T2DM). This study aimed to investigate the …

Objective DPP4, a novel proinflammatory cytokine, is involved in the inflammatory process
through its interaction with the IGF-II/M6P receptor. Our objective was to determine whether …

Abstract Dipeptidyl-peptidase-4 (DPP-4) is an enzyme having various properties and
physiological roles in lipid accumulation, resistance to anticancer agents, and immune …

Dipeptidyl peptidase-4 (DPP-4) has an important role in the carbohydrate metabolism with
the degradation of incretin hormones. Aim: We assessed the serum DPP-4 activity both in …

A novel approach for treatment of type 2 diabetes is based on the gut hormone glucagon-
like peptide-1 (GLP-1), which is antidiabetic due to its combined action to stimulate insulin …

Aims/hypothesis Inhibition of the enzyme dipeptidyl peptidase 4 (DPP-4), which cleaves and
inactivates glucagon-like peptide 1 (GLP-1), is a glucose-lowering strategy in type 2 …