Glucagon-like peptide-1 levels and dipeptidyl peptidase-4 activity in type 2 diabetes
A Senyigit, O Tabak, T Orhanoglu… - Clinical and …, 2017 - utpjournals.press
Purpose Hyperglycemia is the major risk factor for microvascular complications in type 2
diabetes mellitus (T2DM) patients. This randomized controlled clinical trial aimed to …
diabetes mellitus (T2DM) patients. This randomized controlled clinical trial aimed to …
DPP3: from biomarker to therapeutic target of cardiovascular diseases
P Ye, W Duan, YQ Leng, YK Wang, X Tan… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular disease is the leading cause of death globally among non-communicable
diseases, which imposes a serious socioeconomic burden on patients and the healthcare …
diseases, which imposes a serious socioeconomic burden on patients and the healthcare …
Dysregulation of DPP4 is associated with the AMPK/JAK2/STAT3 pathway in adipocytes under insulin resistance status and liraglutide intervention
F Cheng, G Yuan, J He, Y Shao, J Zhang… - … Syndrome and Obesity …, 2019 - Taylor & Francis
Purpose Dipeptidyl peptidase 4 (DPP4) is one of the newly identified adipokines, which acts
as paracrine in adipose tissue and as endocrine hormones in the liver, muscles and central …
as paracrine in adipose tissue and as endocrine hormones in the liver, muscles and central …
Role of DPP4 and DPP4i in Glucose Homeostasis and Cardiorenal Syndrome
SP Panda - Endocrine, Metabolic & Immune Disorders-Drug …, 2023 - ingentaconnect.com
The objective of the review led to the pursuit of adopting dipeptidyl peptidase-4 inhibitors
(DPP4i) as a novel pharmacotherapy in diabetes mellitus (DM) and cardiorenal syndrome …
(DPP4i) as a novel pharmacotherapy in diabetes mellitus (DM) and cardiorenal syndrome …
Circulating sDPP-4 is increased in obesity and insulin resistance but is not related to systemic metabolic inflammation
N Rohmann, K Schlicht, C Geisler… - The Journal of …, 2021 - academic.oup.com
Abstract Context Dipeptidylpeptidase (DPP)-4 is a key regulator of the incretin system. It
exists in a membrane-bound form and a soluble form (sDPP-4). Initial human studies …
exists in a membrane-bound form and a soluble form (sDPP-4). Initial human studies …
Comparison of the dipeptidyl peptidase-4 gene methylation levels between severely obese subjects with and without the metabolic syndrome
Background The dipeptidyl peptidase-4 (DPP4) enzyme is a novel adipokine potentially
involved in the development of the metabolic syndrome (MetS). Previous observations …
involved in the development of the metabolic syndrome (MetS). Previous observations …
The efficacy and safety of DPP4 inhibitors in patients with type 1 diabetes: a systematic review and meta-analysis
H Guo, C Fang, Y Huang, Y Pei, L Chen, J Hu - Diabetes Research and …, 2016 - Elsevier
Abstract Aims Dipeptidyl peptidase-4 (DPP4) inhibitors are a novel class of antidiabetic
medication in the treatment of type 2 diabetes mellitus. Several studies have indicated that …
medication in the treatment of type 2 diabetes mellitus. Several studies have indicated that …
Dipeptidyl peptidase-4 at the interface between inflammation and metabolism
NA Trzaskalski, E Fadzeyeva… - Clinical Medicine …, 2020 - journals.sagepub.com
Dipeptidyl peptidase-4 (DPP4) is a serine protease that rapidly inactivates the incretin
peptides, glucagon-like peptide-1, and glucose-dependent insulinotropic polypeptide to …
peptides, glucagon-like peptide-1, and glucose-dependent insulinotropic polypeptide to …
[HTML][HTML] Immunomodulatory activity of DPP4
S Mamgain, S Mathur, P Kothiyal - Journal of Pharmacology & …, 2013 - calonmedical.com
Dipeptidyle peptidase (DPP4) is the enzyme which is known to break down two gut
hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic …
hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic …
[HTML][HTML] Serum dipeptidyl peptidase-4 activity and progranulin level in polycystic ovary syndrome patients
M Abolghasemi, S Mahjoub… - Caspian Journal of …, 2022 - ncbi.nlm.nih.gov
Background: Evidence showed that abnormal alteration of adipokines level may perform a
key role in polycystic ovary syndrome (PCOS) pathogenesis. Dipeptidyl peptidase-4 (DPP4) …
key role in polycystic ovary syndrome (PCOS) pathogenesis. Dipeptidyl peptidase-4 (DPP4) …