Diabetes mellitus (DM) is a chronic disease which caused around 1.5 million deaths in
2012. Type 2 diabetes mellitus (T2DM) accounts for 90% of DM worldwide. The prevalence …

Aim: Adipokines are the proteins secreted from adipose tissue and play an important role in
the control of metabolism. Dipeptidyl peptidase-4 (DPP4) is a novel adipokine with different …

Abstract Dipeptidyl peptidase 4 (DPP4), also known as CD26 is a type II transmembrane
protein that is released from the cell membrane in a nonclassical secretory mechanism. This …

Type 2 diabetes mellitus is a metabolic disease leading to microvascular and macrovascular
complications including coronary artery disease and stroke. Management of diabetes has …

The number of pregnant women affected by gestational diabetes mellitus (GDM) is
increasing among Caucasians, and East Asians. GDM also increases the risk for later …

Objective. Several clinical studies have reported the application of dipeptidyl peptidase‐4
(DPP‐4) inhibitors as treatments for type 1 diabetes mellitus (T1DM). This study aims to …

Dipeptidyl peptidase IV (DPP-4), an incretin glucagon-like peptide-1 (GLP-1) degrading
enzyme, contains two forms and it can exert various physiological functions particular in …

Background: Evidence showed that abnormal alteration of adipokines level may perform a
key role in polycystic ovary syndrome (PCOS) pathogenesis. Dipeptidyl peptidase-4 (DPP4) …

Dipeptidylpeptidase-4 (DPP-4) is a ubiquitously expressed transmembrane protein that
removes NH2-terminal dipeptides from various substrate hormones, chemokines …

In the 1990s it was discovered that the enzyme dipeptidyl peptidase-4 (DPP-4) inactivates
the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent …