The liver displays an outstanding wound healing and regenerative capacity unmatched by
any other organ. This reparative response is governed by a complex network of …

The epidermal growth factor receptor (EGFR) is a transmembrane receptor tyrosine kinase
that is activated by several ligands leading to the activation of diverse signaling pathways …

Epidemiological studies have established that many tumours occur in association with
persistent inflammation. One clear example of inflammation-related cancer is hepatocellular …

Hepatocellular carcinoma (HCC) is a major cause of cancer‐related deaths. This
malignancy is often diagnosed at an advanced state, when most potentially curative …

Different data support a role for the epidermal growth factor receptor (EGFR) pathway during
liver regeneration and hepatocarcinogenesis. However, important issues, such as the …

Hepatocarcinogenesis is a complex multistep process in which many different molecular
pathways have been implicated. Hepatocellular carcinoma (HCC) is refractory to …

Mice lacking the EGF receptor (EGFR) die between midgestation and postnatal day 20 with
various defects in neural and epithelial organs. Here, we generated mice carrying a floxed …

Hepatocellular carcinoma (HCC) is a frequent cancer with limited treatment options and
poor prognosis. Tumorigenesis has been linked with macrophage-mediated chronic …

Epidermal growth factor receptor (EGFR) is conventionally known to play a crucial role in
hepatocyte proliferation, liver regeneration and is also associated with hepatocellular …

Despite the well‐known hepatoprotective role of the epidermal growth factor receptor
(EGFR) pathway upon acute damage, its specific actions during chronic liver disease …