A general question in development is how do adjacent primordia adopt different
developmental fates and stably maintain their distinct fates? In Drosophila melanogaster, the …

The Drosophila head vertex is composed of three ocelli, stereotypic bristle patterns and
characteristic cuticles. It is derived from the fusion of two eye-antenna discs. The head vertex …

Abstract The Decapentaplegic and Notch signaling pathways are thought to direct regional
specification in the Drosophila eye-antennal epithelium by controlling the expression of …

In Drosophila, the eye and antenna originate from a single epithelium termed the eye-
antennal imaginal disc. Illumination of the mechanisms that subdivide this epithelium into …

In Drosophila, the eye primordium is specified as a subdomain of the larval eye disc. Here,
we show that the Zn-finger transcription factor teashirt (tsh) marks the region of the early eye …

A common occurrence in metazoan development is the rise of multiple tissues/organs from a
single uniform precursor field. One example is the anterior forebrain of vertebrates, which …

The formation of different structures in Drosophila depends on the combined activities of
selector genes and signaling pathways. For instance, the antenna requires the selector …

The homeobox gene orthodenticle (otd) controls the process of regional specification that
takes place in the Drosophila eye-antennal disc during ocelli development. Mutations that …

The eye-antennal disc of Drosophila is composed of three cell layers: a columnar epithelium
called the disc proper (DP); an overlying sheet of squamous cells called the peripodial …

The Drosophila adult head mostly derives from the composite eye-antenna imaginal disc.
The antennal disc gives rise to two adult olfactory organs: the antennae and maxillary palps …