HIV Infected African Children: Gut microbiota in relation to chronic lung disease and long-term antibiotic treatment

TT Flygel - 2024 - munin.uit.no
More than half of the population with HIV in the world live in sub-Saharan Africa. HIV-
associated chronic lung disease is the most prevalent comorbidity among children and …

Composition of gut microbiota of children and adolescents with perinatal HIV infection taking antiretroviral therapy in Zimbabwe

Breathe Study Team - The Journal of …, 2020 - research-repository.uwa.edu.au
BACKGROUND: HIV infection causes impairment of the gastrointestinal barrier, with
substantial depletion of CD4+ T-cells in the gut. Antiretroviral therapy (ART) restores CD4+ …

HIV-infection in children and adolescents in Zimbabwe: viral suppression, airway abnormalities and gut microbiota.

E Sovershaeva - 2019 - munin.uit.no
Sub-Saharan Africa remains the region with the highest burden of HIV among both children
and adults. Access to antiretroviral therapy (ART) has improved survival, yet data on long …

Composition of gut microbiota of children and adolescents with perinatal human immunodeficiency virus infection taking antiretroviral therapy in Zimbabwe

TT Flygel, E Sovershaeva… - The Journal of …, 2020 - academic.oup.com
Background Human immunodeficiency virus (HIV) infection causes impairment of the
gastrointestinal barrier, with substantial depletion of CD4+ T cells in the gut. Antiretroviral …

Distinct lung microbiota associate with HIV-associated chronic lung disease in children

S Bhadriraju, DW Fadrosh, MK Shenoy, DL Lin… - Scientific Reports, 2020 - nature.com
Chronic lung disease (CLD) is a common co-morbidity for HIV-positive children and
adolescents on antiretroviral therapy (ART) in sub-Saharan Africa. In this population, distinct …

Alteration of the gut fecal microbiome in children living with HIV on antiretroviral therapy in Yaounde, Cameroon

WB Abange, C Martin, AJ Nanfack, LG Yatchou… - Scientific Reports, 2021 - nature.com
Multiple factors, such as immune disruption, prophylactic co-trimoxazole, and antiretroviral
therapy, may influence the structure and function of the gut microbiome of children infected …

The effect of long-term azithromycin treatment on the respiratory microbiota of HIV-infected children with chronic lung disease

RE Abotsi - 2022 - open.uct.ac.za
Background: HIV-associated chronic lung disease (HCLD), predominantly obliterative
bronchiolitis, affects more than 30% of perinatally HIV-infected children in Sub-Saharan …

Pediatric perspective: the microbiome in vertical HIV-infection: unravelling gaps, challenges, and therapeutic potential

T Sainz, G Aldrovandi - Current Opinion in HIV and AIDS, 2024 - journals.lww.com
Therapeutic interventions aimed at modulating the gut microbiome in children with HIV have
shown limited impact, and their ability to induce long-term microbiome changes remains …

Alterations in children's sub-dominant gut microbiota by HIV infection and anti-retroviral therapy

QT Nguyen, A Ishizaki, X Bi, K Matsuda, LV Nguyen… - Plos one, 2021 - journals.plos.org
Objective We investigated the impact of human immunodeficiency virus (HIV) infection and
anti-retroviral therapy (ART) on the gut microbiota of children. Design This cross-sectional …

Azithromycin shapes the airway microbiome to improve lung function in HIV-associated lung disease

RE Abotsi, FS Dube, AM Rehman, S Claassen-Weitz… - 2023 - researchsquare.com
HIV-associated chronic lung disease (HCLD) is responsible for over half of all HIV-related
deaths in children. Long-term treatment with the antibiotic azithromycin can reduce the …