Inhibition of vascular endothelial growth factor-induced angiogenesis by resveratrol through interruption of Src-dependent vascular endothelial cadherin tyrosine …

MT Lin, ML Yen, CY Lin, ML Kuo - Molecular pharmacology, 2003 - ASPET
Resveratrol, a polyphenolic compound found in grapes and other fruits, has been reported
to inhibit angiogenesis with an as yet elusive mechanism. Here, we investigate the detailed …

Binding of resveratrol to vascular endothelial growth factor suppresses angiogenesis by inhibiting the receptor signaling

WH Hu, R Duan, YT Xia, QP Xiong… - Journal of agricultural …, 2018 - ACS Publications
Resveratrol is a polyphenol commonly found in plants and food health products, such as
grape and red wine, and was identified for its binding to vascular endothelial growth factor …

Resveratrol modulates angiogenesis through the GSK3β/β-catenin/TCF-dependent pathway in human endothelial cells

H Wang, H Zhou, Y Zou, Q Liu, C Guo, G Gao… - Biochemical …, 2010 - Elsevier
Vascular endothelial growth factor (VEGF) plays a critical role in angiogenesis due to its
potent and specific ability to promote the proliferation and migration of endothelial cells …

Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes

E Brâkenhielm, R Cao, Y Cao - The FASEB Journal, 2001 - Wiley Online Library
ABSTRACT Resveratrol (3, 5, 4′‐trihydroxystilbene) is a natural compound found in
several plants, including grapes, peanuts, and pines, and in their related products. Red wine …

Anti-angiogenic activity of resveratrol, a natural compound from medicinal plants

YU Cao, ZD Fu, F Wang, HY Liu… - Journal of Asian natural …, 2005 - Taylor & Francis
Resveratrol (3, 4′, 5-trihydroxy-trans-stilbene), a naturally occurring phytoalexin found in
grapes and wine, possesses cancer-preventive activity. Angiogenesis is a crucial step in the …

Anti-angiogenic effects of resveratrol mediated by decreased VEGF and increased TSP1 expression in melanoma-endothelial cell co-culture

V Trapp, B Parmakhtiar, V Papazian, L Willmott… - Angiogenesis, 2010 - Springer
Resveratrol, a naturally occurring polyphenol, has been reported to be an anti-tumor and
chemopreventive agent. Recent data show that it may also exert anti-angiogenic effects. We …

Resveratrol derivative, trans‐3,5,4′‐trimethoxystilbene, exerts antiangiogenic and vascular‐disrupting effects in zebrafish through the downregulation of VEGFR2 …

D Alex, EC Leong, ZJ Zhang, GTH Yan… - Journal of cellular …, 2010 - Wiley Online Library
Angiogenesis plays an important role in the development of neoplastic diseases such as
cancer. Resveratrol and its derivatives exert antiangiogenic effects, but the mechanisms of …

Antiatherogenic effect of resveratrol attributed to decreased expression of ICAM-1 (Intercellular adhesion Molecule-1) mechanistic link from focal adhesion to …

Y Seo, J Park, W Choi, D Ju Son… - … , and vascular biology, 2019 - Am Heart Assoc
Objective—Increasing evidence shows that resveratrol has antiatherogenic effects, but its
underlying mechanisms are unknown. Thus, we evaluated the molecular mechanisms …

Inhibition of neointimal formation by trans‐resveratrol: Role of phosphatidyl inositol 3‐kinase‐dependent Nrf2 activation in heme oxygenase‐1 induction

JW Kim, SC Lim, MY Lee, JW Lee… - Molecular nutrition & …, 2010 - Wiley Online Library
Neointima, defined as abnormal growth of the intimal layer of blood vessels, is believed to
be a critical event in the development of vascular occlusive disease. Although resveratrol's …

Resveratrol inhibits angiotensin II-and epidermal growth factor-mediated Akt activation: role of Gab1 and Shp2

UGB Haider, TU Roos, MI Kontaridis, BG Neel… - Molecular …, 2005 - ASPET
trans-Resveratrol (RV), a polyphenolic stilbene derivative found in grape skin and other food
products, has been proposed to exert beneficial effects in cardiovascular disease. Our group …