OBJECTIVE: This study aimed to investigate the effect of oral administration of naringenin in
combination with an aqueous mixture of coconut water (CW) and Arabic gum (AG) on renal …

Background Gentamicin is an effective aminoglycoside antibiotic employed against severe
Gram-negative bacterial infections, but induction of nephrotoxicity limits its frequent clinical …

Aim Gentamicin (GM) is one of the commonest causes of drug‐induced nephrotoxicity.
Moreover, oxidative stress plays an important role in gentamicin‐induced nephrotoxicity …

In this study, the modulator effect of allicin on the oxidative nephrotoxicity of gentamicin in
the kidneys of rats was investigated by determining indices of lipid peroxidation and the …

Methotrexate (MTX) is a drug used in the treatment of various types of cancer and
inflammatory diseases, but its clinical use has been restricted due to its toxicity. Apigenin …

This study was the first to evaluate the possible protective effects of cinnamic acid (CA)
against Gentamicin (GM) induced liver and kidney dysfunctions in rats. Adult male Wistar …

Gentamicin is an effective antibiotic that has been used worldwide for many years. While
considered an essential medicine by the WHO, gentamicin can also lead to severe kidney …

Objectives: Nephrotoxicity is a renal-specific situation in which the excretion of toxic
metabolites is reduced due to toxic agents and drugs. Gentamicin is an antibiotic belongs to …

Kidney injury is a relatively common complication of the use of aminoglycosides.
Inflammation and oxidative stress play a key role in gentamicin (GM) nephrotoxicity. We …

Gentamicin-induced nephrotoxicity has been well documented, although its underlying
mechanisms and preventive strategies remain to be investigated. The present study was …