Post-translational regulation of neuronal nitric oxide synthase: implications for sympathoexcitatory states

NM Sharma, KP Patel - Expert opinion on therapeutic targets, 2017 - Taylor & Francis
Introduction: Nitric oxide (NO) synthesized via neuronal nitric oxide synthase (nNOS) plays a
significant role in regulation/modulation of autonomic control of circulation. Various …

Neuronal nitric oxide synthase and sympathetic nerve activity in neurovascular and metabolic systems

Y Wang, J Golledge - Current neurovascular research, 2013 - ingentaconnect.com
Nitric oxide, derived from nitric oxide synthase (NOS), plays an important role in regulating
sympathetic nerve activity. Neuronal NOS (nNOS) is expressed throughout the central and …

Role of neuronal nitric oxide synthase on cardiovascular functions in physiological and pathophysiological states

A Ally, I Powell, MM Ally, K Chaitoff, SM Nauli - Nitric Oxide, 2020 - Elsevier
This review describes and summarizes the role of neuronal nitric oxide synthase (nNOS) on
the central nervous system, particularly on brain regions such as the ventrolateral medulla …

Molecular mechanisms of neuronal nitric oxide synthase in cardiac function and pathophysiology

YH Zhang, CZ Jin, JH Jang… - The Journal of physiology, 2014 - Wiley Online Library
Neuronal nitric oxide synthase (nNOS or NOS1) is the major endogenous source of
myocardial nitric oxide (NO), which facilitates cardiac relaxation and modulates contraction …

Nitric oxide‐mediated posttranslational modifications: impacts at the synapse

SA Bradley, JR Steinert - Oxidative medicine and cellular …, 2016 - Wiley Online Library
Nitric oxide (NO) is an important gasotransmitter molecule that is involved in numerous
physiological processes throughout the nervous system. In addition to its involvement in …

Cardiac neurobiology of nitric oxide synthases

EJ Danson, DJ Paterson - Annals of the New York Academy of …, 2005 - Wiley Online Library
Nitric oxide (NO) is a potent modulator of cardiac and vascular regulation. Its role in cardiac‐
autonomic neural signaling has received much attention over the last decade because of the …

Dysfunctional and dysregulated nitric oxide synthases in cardiovascular disease: mechanisms and therapeutic potential

R Roy, J Wilcox, AJ Webb, K O'Gallagher - International Journal of …, 2023 - mdpi.com
Nitric oxide (NO) plays an important and diverse signalling role in the cardiovascular system,
contributing to the regulation of vascular tone, endothelial function, myocardial function …

Neuronal nitric oxide synthase

KM Arami, B Jameie, SA Moosavi - Nitric oxide synthase: simple …, 2017 - books.google.com
Nitric oxide synthase (NOS), a flavo‐hemoprotein, regulates nitric oxide (NO) synthesis that
has dual biological activities: as an important signalling molecule in vasodilatation and …

Nitric oxide signalling in the brain and its control of bodily functions

K Chachlaki, V Prevot - British Journal of Pharmacology, 2020 - Wiley Online Library
Nitric oxide (NO) is a versatile molecule that plays key roles in the development and survival
of mammalian species by endowing brain neuronal networks with the ability to make …

Neuronal nitric oxide synthase in hypertension–an update

YH Zhang - Clinical hypertension, 2016 - Springer
Hypertension is a prevalent condition worldwide and is the key risk factor for fatal
cardiovascular complications, such as stroke, sudden cardiac death and heart failure …