Changes in DNA methylation induced by multi-walled carbon nanotube exposure in the workplace

M Ghosh, D Öner, K Poels, AM Tabish… - …, 2017 - Taylor & Francis
This study was designed to assess the epigenetic alterations in blood cells, induced by
occupational exposure to multi-wall carbon nanotubes (MWCNT). The study population …

Epigenetic effects of carbon nanotubes in human monocytic cells

D Öner, M Moisse, M Ghosh, RC Duca, K Poels… - …, 2017 - academic.oup.com
Carbon nanotubes (CNTs) are fibrous carbon-based nanomaterials with a potential to cause
carcinogenesis in humans. Alterations in DNA methylation on cytosine–phosphate …

Alterations in DNA methylation corresponding with lung inflammation and as a biomarker for disease development after MWCNT exposure

TA Brown, JW Lee, A Holian, V Porter… - …, 2016 - Taylor & Francis
Use of multi-walled carbon nanotubes (MWCNT) is growing which increases occupational
exposures to these materials. Their toxic potential makes it important to have an in-depth …

Increased telomere length and mtDNA copy number induced by multi-walled carbon nanotube exposure in the workplace

M Ghosh, L Janssen, DS Martens, D Öner… - Journal of hazardous …, 2020 - Elsevier
Carbon nanotubes (CNTs) except MWCNT-7 have been classified as Group 3 [“Not
classifiable as to its carcinogenicity to humans”] by the IARC. Despite considerable …

Differences in MWCNT-and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

D Öner, M Ghosh, H Bové, M Moisse, B Boeckx… - Particle and fibre …, 2018 - Springer
Background Subtle DNA methylation alterations mediated by carbon nanotubes (CNTs)
exposure might contribute to pathogenesis and disease susceptibility. It is known that both …

Carbon nanotube-and asbestos-induced DNA and RNA methylation changes in bronchial epithelial cells

E Emerce, M Ghosh, D Öner, RC Duca… - Chemical Research …, 2019 - ACS Publications
Carbon nanotubes (CNTs) are nanoscale tube-shaped carbon materials used in many
industrial areas. Their fiber shape has caused concerns about their toxicity given their …

Multiwalled carbon nanotubes of varying size lead to DNA methylation changes that correspond to lung inflammation and injury in a mouse model

E Cole, JL Ray, S Bolten, RF Hamilton Jr… - Chemical Research …, 2019 - ACS Publications
Diversity in physicochemical properties of engineered multiwalled carbon nanotubes
(MWCNTs) increases the complexity involved in interpreting toxicity studies of these …

Hypermethylation and low expression of FANCC involved in multi-walled carbon nanotube-induced toxicity on ARPE-19 cells

Y Liang, Y Zhou, D Xie, F Yin, X Luo - Environmental Research, 2024 - Elsevier
Highlights•First study evaluated DNA methylation profile in MWCNT-exposed ARPE-19
cells.•Six methylation-driven genes were found important for MWCNT exposure.• …

[HTML][HTML] Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice

G Scala, MN Delaval, SP Mukherjee, A Federico… - Carbon, 2021 - Elsevier
Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) causes inflammation and
fibrosis. Our previous work has shown that industrially produced MWCNTs trigger specific …

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes

MI Sierra, L Rubio, GF Bayón, I Cobo… - …, 2017 - Taylor & Francis
Humans are increasingly exposed to nanoparticles and, although many of their
physiological effects have been described, the molecular mechanisms underlying them are …