Skeletal muscles cope with a large range of activities, from being able to support the body
weight during long periods of upright standing to perform explosive movements in response …

Energy deprivation poses a tremendous challenge to skeletal muscle. Glucose (ATP)
depletion causes muscle fibers to undergo rapid adaptive changes toward the use of fatty …

The plasticity of skeletal muscle, whether an increase in size, change in metabolism, or
alteration in structural properties, is in a continuous state of flux largely dependent upon …

Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …

Mammalian skeletal muscles are composed of a variety of highly specialized fibers whose
selective recruitment allows muscles to fulfill their diverse functional tasks. In addition …

Skeletal muscle is one of the most dynamic and plastic tissues of the human body. In
humans, skeletal muscle comprises approximately 40% of total body weight and contains 50 …

Skeletal and cardiac muscles play key roles in the regulation of systemic energy
homeostasis and display remarkable plasticity in their metabolic responses to caloric …

Skeletal muscles share many common, highly conserved features of organization at the
molecular and myofilament levels, giving skeletal muscle fibers generally similar and …

Skeletal muscles are used in several different ways. Often they form variable-length struts,
stiffening joints and appendages for such tasks as standing or holding objects. During …

Biological systems have acquired effective adaptive strategies to cope with physiological
challenges and to maximize biochemical processes under imposed constraints. Striated …