This randomized, double-blind, crossover study aimed to determine if acute treatment with
inhaled bronchodilators, by improving regional lung hyperinflation and ventilation …

The use of bronchodilator drugs to reduce the symptoms and increase the exercise
tolerance of patients with chronic obstructive pulmonary disease (COPD) is a cornerstone of …

We investigated whether dual bronchodilator therapy (glycopyrrolate/formoterol fumarate;
GFF; Bevespi Aerosphere) would increase exercise tolerance during a high-intensity …

Exercise tolerance is an important parameter in patients with COPD and a primary goal of
treatment is to reduce dyspnea to facilitate physical activities and improve health-related …

Background: Patients with symptoms of GOLD stage I chronic obstructive pulmonary disease
(COPD) can have significant abnormalities of ventilatory mechanics with greater exertional …

Study objective To evaluate the impact of a week-long course of inhaled albuterol compared
with ipratropium on expiratory peak flow, exercise performance, and dyspnea in patients …

INTRODUCTION: Pulmonary dynamic hyperinflation (DH) is an important factor limiting the
physical capacity of patients with COPD. Inhaled bronchodilator should be able to reduce …

Background Many patients with chronic obstructive pulmonary disease continue to
experience significant functional limitation despite the use of both long-acting anticholinergic …

Although long-acting inhaled β2-agonists improve various outcome measures in COPD, no
double-blind study has yet shown a significant effect of these drugs on exercise capacity. In …

Introduction Inhaled anticholinergic drugs are often recommended for use as a first-line
therapy for patients with COPD because they provide similar or more effective …