Prepulse inhibition (PPI) is a measure of sensorimotor gating that is deficient in
schizophrenia. In rats, administration of the serotonin-1A (5-HT1A) receptor agonist, 8 …

Recent studies have implicated central serotonergic systems in the modulation of prepulse
inhibition (PPI), an operational measure of sensorimotor gating, which has been used to …

Prepulse inhibition (PPI) is a measure of sensorimotor gating and an endophenotype of
schizophrenia. We have shown previously in rats that estrogen treatment prevents disruption …

Background and purpose: Prepulse inhibition (PPI) of the acoustic startle response is a
model of sensorimotor gating which is disrupted in schizophrenia and other mental …

Abstract The 5-hydroxytryptamine 2A (5-HT 2A) receptor plays an important role in
schizophrenia. The 5-HT 2A receptor is also involved in the regulation of prepulse inhibition …

Serotonin-1A (5-HT1A) receptors have been implicated in the symptoms of schizophrenia.
However, there is limited in vivo evidence for an interaction of antipsychotic drugs with 5 …

Prepulse inhibition (PPI) is a measure of sensorimotor gating and an endophenotype of
schizophrenia. We have previously shown that estrogen treatment prevents disruption of PPI …

Abstract The 5-HT 1A agonist 8-OH-DPAT has been reported to disrupt prepulse inhibition
(PPI) of the acoustic startle reflex after local administration into the raphe nuclei. Because it …

This study aimed to explore strain and species differences in the involvement of 5-HT 1A
receptors in the action of antipsychotic drugs, using prepulse inhibition (PPI), a model of …

Prepulse inhibition (PPI) is a model of sensorimotor gating, a sensory filtering mechanism
which is disrupted in schizophrenia. Here, investigation of the role of the serotonin-1A (5 …