Cell‐surface sialic acids are essential in mediating a variety of physiological and
pathological processes. Sialic acid chemistry and biology remain challenging to investigate …

Sialic acid analogues containing a unique chemical functionality or chemical reporter have
been metabolically incorporated into sialylated glycans. This process, termed metabolic …

Sialic acids cap the glycans of cell surface glycoproteins and glycolipids. They are involved
in a multitude of biological processes, and aberrant sialic acid expression is associated with …

This report provides a perspective on metabolic glycoengineering methodology developed
over the past two decades that allows natural sialic acids to be replaced with chemical …

Sialic acids cap the glycans of cell surface glycoproteins and glycolipids. They are involved
in a multitude of biological processes and aberrant sialic acid expression is associated with …

Sialic acids have diverse biological roles, ranging from promoting up to preventing protein
and cellular recognition in health and disease. The various functions of these …

Exo-enzymatic glycan labeling strategies have emerged as versatile tools for efficient and
selective installation of terminal glyco-motifs onto live cell surfaces. Through employing …

N-Acetylneuraminic acid is the most prominent sialic acid in eukaryotes. The structural
diversity of sialic acid is exploited by viruses, bacteria, and toxins and by the …

Sialoglycans play a vital role in physiology, and aberrant sialoglycan expression is
associated with a broad spectrum of diseases. Since biosynthesis of sialoglycans is only …

The analysis of sialylated glycans is critical for understanding the role of sialic acid in normal
biological processes as well as in disease. However, the labile nature of sialic acid typically …