A new hazard index of complex mixtures integrates bioconcentration and toxicity to refine the environmental risk assessment of effluents

S Gutiérrez, C Fernández, BI Escher… - Environment international, 2008 - Elsevier
A new methodology to evaluate the overall environmental hazard of unknown mixtures,
based on bioconcentration potential and toxicity, was developed using a combination of two …

Mixture toxicity prediction of substances from different origin sources in Daphnia magna

ARR Silva, SF Gonçalves, MD Pavlaki, RG Morgado… - Chemosphere, 2022 - Elsevier
Due to several anthropogenic activities, water bodies have been heavily impacted by
contaminants identified in aquatic ecosystems, including pharmaceuticals, personal care …

Prospective environmental risk assessment of mixtures in wastewater treatment plant effluents–theoretical considerations and experimental verification

A Coors, P Vollmar, F Sacher, C Polleichtner… - Water research, 2018 - Elsevier
The aquatic environment is continually exposed to a complex mixture of chemicals, whereby
effluents of wastewater treatment plants (WWTPs) are one key source. The aim of the …

Toxicity assessment of environmentally relevant pollutant mixtures using a heuristic model

AW Olmstead, GA LeBlanc - … Environmental Assessment and …, 2005 - Wiley Online Library
In this study, 9 chemicals were chosen from a recent report on surface water concentrations
of a variety of xenobiotics to test the hypothesis that the toxicity of chemical mixtures could …

Predictive assessment of the aquatic toxicity of multiple chemical mixtures

M Faust, R Altenburger, T Backhaus, W Bödeker… - 2000 - Wiley Online Library
Current approaches to the assessment of chemical hazards focus on toxicity studies with
single, pure chemicals. In the environment, however, organisms are exposed to numerous …

Assessment of multi-chemical pollution in aquatic ecosystems using toxic units: compound prioritization, mixture characterization and relationships with biological …

A Ginebreda, M Kuzmanovic, H Guasch… - Science of the total …, 2014 - Elsevier
Chemical pollution is typically characterized by exposure to multiple rather than to single or
a limited number of compounds. Parent compounds, transformation products and other non …

Are current regulatory log Kow cut-off values fit-for-purpose as a screening tool for bioaccumulation potential in aquatic organisms?

S Gimeno, D Allan, K Paul, P Remuzat… - Regulatory Toxicology …, 2024 - Elsevier
Abstract Persistent, Bioaccumulative and Toxic (PBT) and very Persistent and very
Bioaccumulative (vPvB) are regulatory hazard categories that have been set to manage the …

Repeatability of n-octanol/water partition coefficient values between liquid chromatography measurement methods

P Saranjampour, K Armbrust - Environmental Science and Pollution …, 2018 - Springer
The n-octanol/water partition coefficient (K OW) is a physical/chemical property that is
extensively used for regulatory and environmental risk and exposure assessments. The K …

The'whole-effluent'toxicity approach

T Tisler, J Zagorc-Koncan - International Journal of …, 2007 - inderscienceonline.com
The identification and quantification of effluent toxicity plays an important role in the
evaluation of harmful impacts on the aquatic environment. The aim of this study was to …

Sensitivity of schemes for ecotoxicological hazard ranking of chemicals

W Klein, H Geyer, D Freitag, H Rohleder - Chemosphere, 1984 - Elsevier
Data from an environmental hazard profile, including different tests on accumulation and
degradation as well as Daphnia acute toxicity were used for a classification of chemicals into …