Minimal self-replicating systems
A Robertson, AJ Sinclair, D Philp - Chemical Society Reviews, 2000 - pubs.rsc.org
Examples of chemical systems capable of templating and catalysing their own synthesis—
self-replicating systems—have begun to appear in the chemical literature over the last 15 …
self-replicating systems—have begun to appear in the chemical literature over the last 15 …
Making molecules make themselves–the chemistry of artificial replicators
A Vidonne, D Philp - European Journal of Organic Chemistry, 2009 - Wiley Online Library
Examples of chemical systems capable of templating and catalyzing their own synthesis–so‐
called replicating systems–have begun to appear in the chemical literature over the last 20 …
called replicating systems–have begun to appear in the chemical literature over the last 20 …
[HTML][HTML] Towards open-ended evolution in self-replicating molecular systems
In this review we discuss systems of self-replicating molecules in the context of the origin of
life and the synthesis of de novo life. One of the important aspects of life is the ability to …
life and the synthesis of de novo life. One of the important aspects of life is the ability to …
Minimal self-replicating systems
N Paul, GF Joyce - Current opinion in chemical biology, 2004 - Elsevier
Minimal self-replicating systems typically consist of three components: a product molecule,
and two substrate molecules that become joined to form another product molecule. An …
and two substrate molecules that become joined to form another product molecule. An …
Parasitic Behavior of Self‐Replicating Molecules
Self‐replication plays a central role in the origin of life and in strategies to synthesize life de
novo. Studies on self‐replication have focused mostly on isolated systems, while the …
novo. Studies on self‐replication have focused mostly on isolated systems, while the …
Emergence of a new self-replicator from a dynamic combinatorial library requires a specific pre-existing replicator
Our knowledge regarding the early steps in the formation of evolvable life and what
constitutes the minimal molecular basis of life remains far from complete. The recent …
constitutes the minimal molecular basis of life remains far from complete. The recent …
Existing Self‐Replicators Can Direct the Emergence of New Ones
The study of the interplay between different self‐replicating molecules constitutes an
important new phase in the synthesis of life and in unravelling the origin of life. Here we …
important new phase in the synthesis of life and in unravelling the origin of life. Here we …
Synthetic biology: evolution or revolution? A co-founder's perspective
TS Gardner, K Hawkins - Current opinion in chemical biology, 2013 - Elsevier
Highlights•Synthetic Biology emerged in the late 1990s from a convergence of research on
cellular computing.•Its founding premise: standardized biological components will …
cellular computing.•Its founding premise: standardized biological components will …
Chemical fueling enables molecular complexification of self‐replicators
Unravelling how the complexity of living systems can (have) emerge (d) from simple
chemical reactions is one of the grand challenges in contemporary science. Evolving …
chemical reactions is one of the grand challenges in contemporary science. Evolving …
Design and implementation of a highly selective minimal self-replicating system
E Kassianidis, D Philp - … Chemie-International Edition, 2006 - scholars.northwestern.edu
Self-direction: A rationally designed self-complementary template (see picture) is capable of
replication, thereby amplifying itself from a reaction mixture to the exclusion of its …
replication, thereby amplifying itself from a reaction mixture to the exclusion of its …