In contrast to the well-characterized effects of specialized proresolving lipid mediators
(SPMs) derived from eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), little is …

Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …

The role of docosahexaenoic acid (DHA) and arachidonic acid (AA) in neurogenesis and
brain development throughout the life cycle is fundamental. DHA and AA are long-chain …

The n-6 fatty acid arachidonic acid (AA; 20: 4n-6) gives rise to eicosanoid mediators that
have established roles in inflammation and AA metabolism is a long recognised target for …

Epidemiological studies have linked fish oil consumption to a decreased incidence of
cancer. The anticancer effects of fish oil are mostly attributed to its content of omega‐3 fatty …

Dietary ω-3 polyunsaturated fatty acids (PUFAs) decrease cardiovascular risk via
suppression of inflammation. The generation of electrophilic α, β-unsaturated ketone …

Long chain fatty acids influence inflammation through a variety of mechanisms; many of
these are mediated by, or at least associated with, changes in fatty acid composition of cell …

Accumulating evidence indicates that, analogous to n-6 PUFA, n-3 PUFA are enzymatically
converted into diverse families of bioactive mediators that play numerous roles in …

A novel genus of pro-resolving lipid mediators endogenously generated from omega-3
polyunsaturated fatty acids has been identified in exudates obtained during the resolution …

Inflammation plays a key role in many common conditions and diseases. Fatty acids can
influence inflammation through a variety of mechanisms acting from the membrane to the …