Role of n-3 fatty acids in muscle loss and myosteatosis
JB Ewaschuk, A Almasud… - … Physiology, Nutrition, and …, 2014 - cdnsciencepub.com
Image-based methods such as computed tomography for assessing body composition
enables quantification of muscle mass and muscle density and reveals that low muscle …
enables quantification of muscle mass and muscle density and reveals that low muscle …
Targeting the myostatin signaling pathway to treat muscle wasting diseases
HQ Han, WE Mitch - Current opinion in supportive and palliative …, 2011 - journals.lww.com
Muscle wasting increases the risks of morbidity and mortality. But, the reliability of estimates
of the degree of muscle wasting is controversial as are definitions of terms like cachexia …
of the degree of muscle wasting is controversial as are definitions of terms like cachexia …
The vicious cycle of myostatin signaling in sarcopenic obesity: myostatin role in skeletal muscle growth, insulin signaling and implications for clinical trials
LA Consitt, BC Clark - The Journal of frailty & aging, 2018 - Springer
The age-related loss of skeletal muscle (sarcopenia) is a major health concern as it is
associated with physical disability, metabolic impairments, and increased mortality. The …
associated with physical disability, metabolic impairments, and increased mortality. The …
AI-based CT body composition identifies myosteatosis as key mortality predictor in asymptomatic adults
Background Body composition data have been limited to adults with disease or older age.
The prognostic impact in otherwise asymptomatic adults is unclear. Purpose To use artificial …
The prognostic impact in otherwise asymptomatic adults is unclear. Purpose To use artificial …
Ectopic lipid accumulation and reduced glucose tolerance in elderly adults are accompanied by altered skeletal muscle mitochondrial activity
DL Johannsen, KE Conley, S Bajpeyi… - The Journal of …, 2012 - academic.oup.com
Context: Aging is associated with insulin resistance and unfavorable changes in body
composition including increased fat accumulation, particularly in visceral and ectopic …
composition including increased fat accumulation, particularly in visceral and ectopic …
Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …
Measurement of skeletal muscle: laboratory and epidemiological methods
WJ Evans, SB Heymsfield, D Gallagher… - The Journals of …, 1995 - academic.oup.com
Despite skeletal muscle's central role in the pathogenesis of sarcopenia, measurement
methods remain underinvestigated and inadequately validated. Our review indicates that …
methods remain underinvestigated and inadequately validated. Our review indicates that …
Assessing skeletal muscle mass: historical overview and state of the art
Background Even though skeletal muscle (SM) is the largest body compartment in most
adults and a key phenotypic marker of sarcopenia and cachexia, SM mass was until recently …
adults and a key phenotypic marker of sarcopenia and cachexia, SM mass was until recently …
Adipose tissue quality in aging: how structural and functional aspects of adipose tissue impact skeletal muscle quality
The interplay between adipose tissue and skeletal muscle and the impact on mobility and
aging remain enigmatic. The progressive decline in mobility promoted by aging has been …
aging remain enigmatic. The progressive decline in mobility promoted by aging has been …
Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men
A Granic, K Suetterlin, T Shavlakadze… - Clinical …, 2023 - portlandpress.com
Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …