Muscle wasting and aging: experimental models, fatty infiltrations, and prevention

T Brioche, AF Pagano, G Py, A Chopard - Molecular Aspects of Medicine, 2016 - Elsevier
Identification of cost-effective interventions to maintain muscle mass, muscle strength, and
physical performance during muscle wasting and aging is an important public health …

[HTML][HTML] Muscle wasting disease: a proposal for a new disease classification

SD Anker, AJS Coats, JE Morley, G Rosano… - Journal of cachexia …, 2014 - Springer
Muscle wasting and cachexia are the ultimate consequence of aging and a variety of acute
and chronic illnesses. Significant efforts are made by many stakeholders to develop effective …

[HTML][HTML] Human skeletal muscle disuse atrophy: effects on muscle protein synthesis, breakdown, and insulin resistance—a qualitative review

SS Rudrappa, DJ Wilkinson, PL Greenhaff… - Frontiers in …, 2016 - frontiersin.org
The ever increasing burden of an aging population and pandemic of metabolic syndrome
worldwide demands further understanding of the modifiable risk factors in reducing disability …

[HTML][HTML] A metabolic link to skeletal muscle wasting and regeneration

R Koopman, CH Ly, JG Ryall - Frontiers in physiology, 2014 - frontiersin.org
Due to its essential role in movement, insulating the internal organs, generating heat to
maintain core body temperature, and acting as a major energy storage depot, any …

Sarcopenic obesity or obese sarcopenia: a cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the …

A Kalinkovich, G Livshits - Ageing research reviews, 2017 - Elsevier
Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …

The emerging role of skeletal muscle oxidative metabolism as a biological target and cellular regulator of cancer-induced muscle wasting

JA Carson, JP Hardee, BN VanderVeen - Seminars in cell & developmental …, 2016 - Elsevier
While skeletal muscle mass is an established primary outcome related to understanding
cancer cachexia mechanisms, considerable gaps exist in our understanding of muscle …

[HTML][HTML] Modifying muscle mass–the endocrine perspective

AM Solomon, PMG Bouloux - Journal of Endocrinology, 2006 - joe.bioscientifica.com
This review describes the major hormonal factors that determine the balance between
human skeletal muscle anabolism and catabolism in health and disease, with specific …

[HTML][HTML] Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training

K Lenk, G Schuler, V Adams - Journal of cachexia, sarcopenia and muscle, 2010 - Springer
Skeletal muscle is the most abundant tissue in the human body, and the maintenance of its
mass is essential to ensure basic function as locomotion, strength and respiration. The …

[HTML][HTML] From muscle wasting to sarcopenia and myopenia: update 2012

S von Haehling, JE Morley, SD Anker - Journal of cachexia, sarcopenia …, 2012 - Springer
Human muscle undergoes constant changes. After about age 50, muscle mass decreases at
an annual rate of 1–2%. Muscle strength declines by 1.5% between ages 50 and 60 and by …

[HTML][HTML] Longitudinal study of muscle strength, quality, and adipose tissue infiltration

MJ Delmonico, TB Harris, M Visser, SW Park… - The American journal of …, 2009 - Elsevier
Background Sarcopenia is thought to be accompanied by increased muscle fat infiltration.
However, no longitudinal studies have examined concomitant changes in muscle mass …