Small cationic, amphipathic peptides with critical roles in host defenses often exhibit
overlapping but distinct immunomodulatory activity, direct antimicrobial activity towards …

The golden era of antibiotics, heralded by the discovery of penicillin, has long been
challenged by the emergence of antimicrobial resistance (AMR). Host defense peptides …

Host defense peptides (HDPs) are relatively small, mostly cationic, amphipathic, and of
variable length, sequence, and structure. The majority of these peptides exhibit broad …

Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …

Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

Cationic Host Defense Peptides (HDP, also known as antimicrobial peptides) are crucial
components of the innate immune system and possess broad-spectrum antibacterial …

Bacteria predominantly exist as multicellular aggregates known as biofilms that are
associated with at least two thirds of all infections and exhibit increased adaptive resistance …

Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …

Non-natural amino acids can be incorporated into synthetic host defense peptides (HDPs) to
modulate their susceptibility to proteolytic degradation. However, the impact of non-natural …

Health leaders and scientists worldwide consider antibiotic resistance among the world's
most dangerous pathogens as one of the biggest threats to global health. Antibiotic …