Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
REW Hancock, HG Sahl - Nature biotechnology, 2006 - nature.com
Short cationic amphiphilic peptides with antimicrobial and/or immunomodulatory activities
are present in virtually every life form, as an important component of (innate) immune …
are present in virtually every life form, as an important component of (innate) immune …
Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections
A Nijnik, REW Hancock - Emerging health threats journal, 2009 - Taylor & Francis
The rapidly increasing incidence of multidrug-resistant infections and the alarmingly low rate
of discovery of conventional antibiotics create an urgent need for alternative strategies to …
of discovery of conventional antibiotics create an urgent need for alternative strategies to …
Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications
Y Wu, K Chen, J Wang, M Chen, Y Chen, Y She… - Progress in Polymer …, 2023 - Elsevier
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …
countless human lives, however, is seriously challenged by the quick emergence of …
Antimicrobial peptides: therapeutic potential
L Zhang, TJ Falla - Expert opinion on pharmacotherapy, 2006 - Taylor & Francis
A significant component of the innate immune system of a wide variety of animals and plants
is arbitrated by cationic host defence peptides. In man, these peptides, in addition to …
is arbitrated by cationic host defence peptides. In man, these peptides, in addition to …
Cationic host defense (antimicrobial) peptides
KL Brown, REW Hancock - Current opinion in immunology, 2006 - Elsevier
Members of the cationic host defense (antimicrobial) peptide family are widely distributed in
nature, existing in organisms from insects to plants to mammals and non-mammalian …
nature, existing in organisms from insects to plants to mammals and non-mammalian …
[HTML][HTML] Aggregation and its influence on the immunomodulatory activity of synthetic innate defense regulator peptides
There is increasing interest in developing cationic host defense peptides (HDPs) and their
synthetic derivatives as antimicrobial, immunomodulatory, and anti-biofilm agents. These …
synthetic derivatives as antimicrobial, immunomodulatory, and anti-biofilm agents. These …
[HTML][HTML] Defense peptides: recent developments
M Cytryńska, A Zdybicka-Barabas - Biomolecular concepts, 2015 - degruyter.com
Defense peptides are small amphipathic molecules that exhibit antimicrobial, antitumor,
antiviral, and immunomodulatory properties. This review summarizes current knowledge on …
antiviral, and immunomodulatory properties. This review summarizes current knowledge on …
Host defense peptides: front-line immunomodulators
SC Mansour, OM Pena, REW Hancock - Trends in immunology, 2014 - cell.com
Although first studied for their antimicrobial activity, host defense peptides (HDPs) are now
widely recognized for their multifunctional roles in both the innate and adaptive immune …
widely recognized for their multifunctional roles in both the innate and adaptive immune …
Host defense peptides as immunomodulators: The other side of the coin
EM Martell, M Gonzalez-Garcia, L Ständker… - Peptides, 2021 - Elsevier
Host defense peptides (HDPs) exhibit a broad range of antimicrobial and
immunomodulatory activities. In this sense, both functions are like different sides of the same …
immunomodulatory activities. In this sense, both functions are like different sides of the same …
Design of host defence peptides for antimicrobial and immunity enhancing activities
JB McPhee, MG Scott… - Combinatorial chemistry & …, 2005 - ingentaconnect.com
Host defense peptides are a vital component of the innate immune systems of humans, other
mammals, amphibians, and arthropods. The related cationic antimicrobial peptides are also …
mammals, amphibians, and arthropods. The related cationic antimicrobial peptides are also …