Current therapeutic options for Alzheimer's disease

A Lleó - Current genomics, 2007 - ingentaconnect.com
Alzheimer's disease (AD) is the most common neurodegenerative disease in the developed
world. The increasing life expectancy in the last years has led to an increase in the …

Current pharmacotherapy for Alzheimer's disease

A Lleo, SM Greenberg, JH Growdon - Annu. Rev. Med., 2006 - annualreviews.org
Alzheimer's disease (AD) is an age-related neurodegenerative disease that affects
approximately 4.5 million people in the United States. The mainstays of current …

Therapeutic perspectives in Alzheimer's disease

JA Tschape, T Hartmann - Recent Patents on CNS Drug …, 2006 - ingentaconnect.com
It is now almost a century ago that Alois Alzheimer first presented his results in public. Main
characteristics of Alzheimer's disease (AD) are massive cerebral accumulation of amyloid …

Alzheimer's disease: a tangled issue

A Benson - Drug discovery today, 2005 - infona.pl
Diseases of the ageing population, such as Alzheimer's disease, could soon be viewed with
greater dread than other diseases, such as cancer. Unfortunately, although there is a wealth …

A short perspective on the long road to effective treatments for Alzheimer's disease

DS Reynolds - British Journal of Pharmacology, 2019 - Wiley Online Library
Globally, there are approximately 47 million people living with dementia, and about two
thirds of those have Alzheimer's disease (AD). Age is the single biggest risk factor for the …

[图书][B] Alzheimer's Disease: Drug Discovery

X Huang - 2020 - scholar.archive.org
Copyright of individual chapters belongs to the respective authors. The authors grant
unrestricted publishing and distribution rights to the publisher. The electronic versions of the …

Alzheimer's disease: Novel targets and investigational drugs for disease modification

JL Cummings, AML Osse, JW Kinney - Drugs, 2023 - Springer
Novel agents addressing non-amyloid, non-tau targets in Alzheimer's Disease (AD)
comprise 70% of the AD drug development pipeline of agents currently in clinical trials. Most …

Current treatment for Alzheimer disease and future prospects

PN Tariot, HJ Federoff - Alzheimer disease & associated disorders, 2003 - journals.lww.com
A cascade of pathophysiological events is triggered in Alzheimer disease (AD) that
ultimately involves common cellular signaling pathways and leads to cellular and network …

Current therapeutic targets for Alzheimer's disease

A Chaudhary, PK Maurya, BS Yadav, S Singh… - Journal of …, 2018 - jbiomed.com
Alzheimer's disease (AD) is one of the most common multifactorial diseases, including a
range of abnormal cellular/molecular processes occurring in different regions of the brain …

[PDF][PDF] Alzheimer's disease: a molecular mechanism, new hypotheses, and therapeutic strategies

M Plečkaitytė - Medicina, 2010 - pdfs.semanticscholar.org
Human diseases involving protein misfolding and aggregation have received increasing
attention in recent years. Alzheimer's disease and other diseases associated with aging are …