T CELLS recognize foreign proteins as peptides bound to self molecules encoded by the
major histocompatibility complex (MHC) 1. The kinetics of interaction between purified class …

CLASS II major histocompatibility complex (MHC) molecules are heterodimeric cell surface
glycoproteins which bind and present immunogenic peptides to T lymphocytes. Such …

Cytotoxic T lymphocytes (CTLs) recognize class I major histocompatibility complex (MHC)
molecules associated with antigenic peptides derived from endogenously synthesized …

An influenza virus peptide binds to HLA-DR1 in an extended conformation with a
pronounced twist. Thirty-five per cent of the peptide surface is accessible to solvent and …

Staphylococcal enterotoxins (SEs) have been shown to bind to major histocompatibility
complex (MHC) class II proteins and stimulate T cells in a V beta-specific manner, and these …

The class I histocompatibility antigen from human cell membranes has two structural motifs:
the membrane-proximal end of the glycoprotein contains two domains with immunoglobulin …

NEWLY synthesized major histocompatibility complex (MHC) class I molecules in the
endoplasmic reticulum are thought to bind peptides of foreign and endogenous antigens1 …

T CELLS recognize foreign protein antigens in the form of peptide fragments bound tightly to
the outer aspect of molecules encoded by the major histocompatibility complex (MHC). Most …

T-cell receptors (TCRs) are membrane anchored heterodimers structurally related to
antibody molecules. Single-chain antibodies can be engineered by linking the two variable …

The Staphylococcal enterotoxin superantigens stimulate vigorous responses in T cells
bearing certain T cell antigen receptor (TCR) V beta regions. In addition to activation, these …