Evaluation of neutralizing efficacy of monoclonal antibodies specific for 2009 pandemic H1N1 influenza A virus in vitro and in vivo

J Chen, B Yan, Q Chen, Y Yao, H Wang, Q Liu… - Archives of …, 2014 - Springer
Pandemic influenza A virus (H1N1) 2009 poses a serious public-health challenge
worldwide. To characterize the neutralizing epitopes of this virus, we generated a panel of …

[HTML][HTML] Soluble recombinant hemagglutinin protein of H1N1pdm09 influenza virus elicits cross-protection against a lethal H5N1 challenge in mice

S Yamada, A Yasuhara, Y Kawaoka - Frontiers in microbiology, 2019 - frontiersin.org
Currently, influenza vaccines are produced using embryonated chicken eggs. Recently,
recombinant influenza vaccines have been developed as a potential alternative to egg …

Heterosubtypic antibody response elicited with seasonal influenza vaccine correlates partial protection against highly pathogenic H5N1 virus

H Ding, C Tsai, F Zhou, P Buchy, V Deubel, P Zhou - PLoS One, 2011 - journals.plos.org
Background The spread of highly pathogenic avian influenza (HPAI) H5N1 virus in human
remains a global health concern. Heterosubtypic antibody response between seasonal …

Hemagglutinin stalk-and neuraminidase-specific monoclonal antibodies protect against lethal H10N8 influenza virus infection in mice

TJ Wohlbold, V Chromikova, GS Tan, P Meade… - Journal of …, 2016 - Am Soc Microbiol
ABSTRACT Between November 2013 and February 2014, China reported three human
cases of H10N8 influenza virus infection in the Jiangxi province, two of which were fatal …

Neutralizing and protective epitopes of the 2009 pandemic influenza H1N1 hemagglutinin

F Schmeisser, R Friedman, J Besho… - Influenza and other …, 2013 - Wiley Online Library
Aims and Methods To facilitate antigenic characterization of the influenza A 2009 pandemic
H1N1 [A (H1N1) pdm09] hemagglutinin (HA), we generated a panel of murine monoclonal …

A plant‐based system for rapid production of influenza vaccine antigens

Y Shoji, CE Farrance, J Bautista, H Bi… - Influenza and other …, 2012 - Wiley Online Library
Please cite this paper as: Shoji et al.(2011) A plant‐based system for rapid production of
influenza vaccine antigens. Influenza and Other Respiratory Viruses 6 (3), 204–210 …

Cross-reactive fc-fused single-domain antibodies to hemagglutinin stem region protect mice from group 1 influenza a virus infection

DV Voronina, DV Shcheblyakov, IA Favorskaya… - Viruses, 2022 - mdpi.com
The continued evolution of influenza viruses reduces the effectiveness of vaccination and
antiviral drugs. The identification of novel and universal agents for influenza prophylaxis and …

Intranasal delivery of an IgA monoclonal antibody effective against sublethal H5N1 influenza virus infection in mice

J Ye, H Shao, D Hickman, M Angel, K Xu… - Clinical and Vaccine …, 2010 - Am Soc Microbiol
Highly pathogenic avian H5N1 influenza viruses are endemic in poultry in Asia and pose a
pandemic threat to humans. Since the deployment of vaccines against a pandemic strain …

Plant-based rapid production of recombinant subunit hemagglutinin vaccines targeting H1N1 and H5N1 influenza

Y Shoji, JA Chichester, M Jones, SD Manceva… - Human …, 2011 - Taylor & Francis
In 2009, a novel H1N1 swine influenza virus was isolated from infected humans in Mexico
and the United States, and rapidly spread around the world. Another virus, a highly …

A high-affinity CDR-grafted antibody against influenza A H5N1 viruses recognizes a conserved epitope of H5 hemagglutinin

F Xiong, L Xia, J Wang, B Wu, D Wang, L Yuan… - PloS one, 2014 - journals.plos.org
Highly pathogenic avian influenza (HPAI) H5N1 virus infection is still a potential threat to
public health worldwide. While vaccines and antiviral drugs are currently under …