H4 influenza viruses have been isolated from birds across the world. In recent years, an H4
influenza virus infection has been confirmed in pigs. Pigs play an important role in the …

The rapid rate of influenza virus mutation drives the emergence of new strains that inflict
serious seasonal epidemics and less frequent, but more deadly, pandemics. While …

To characterize the antigenic epitopes of the hemagglutinin (HA) protein of H1N1 influenza
virus, a panel consisting of 84 clones of murine monoclonal antibodies (mAbs) were …

Background Continuing transmissions of highly pathogenic H5N1 viruses in poultry and
humans underscores the need for a rapid response to potential pandemic in the form of …

The H7N9 influenza virus causes high-mortality disease in humans but no effective
therapeutics are available. Here we report a human monoclonal antibody, m826, that binds …

Hemagglutinin (HA) is the immunodominant protein of the influenza virus. We previously
showed that mice injected with a monoglycosylated influenza A HA (HAmg) produced cross …

Therapeutic monoclonal antibodies that target the conserved stalk domain of the influenza
virus hemagglutinin and stalk-based universal influenza virus vaccine strategies are being …

Background Recent outbreaks of highly pathogenic H5N1 viruses in humans indicate that
no endogenous protection exists in the general population. Vaccination programmes …

The pandemic caused by the new H1N1 swine-origin influenza virus (S-OIV) strain is a
worldwide health emergency and alternative therapeutic and prophylactic options are …

Influenza A (H1N1) viruses of swine origin were introduced into the human population in
2009 and caused a pandemic. The disease burden in the elderly was relatively low, which …