Rapid characterization of the biomechanical properties of drug-treated cells in a microfluidic device

X Zhang, HK Chu, Y Zhang, G Bai… - Journal of …, 2015 - iopscience.iop.org
Cell mechanics is closely related to many cell functions. Recent studies have suggested that
the deformability of cells can be an effective biomarker to indicate the onset and progression …

Analysis of red blood cell deformability using parallel ladder electrodes in a microfluidic manipulation system

W Li, B Zhu, Y Cai, Z Wu, L Sun, H Yang - The International Journal of …, 2019 - Springer
The mechanical properties of biological cells are known as effective label-free biomarkers in
many cell physiological events. Several techniques have been proposed to manipulate …

Dielectrophoresis‐based method for measuring the multiangle mechanical properties of biological cells

B Zhu, W Li, M Zhu, PL Hsu, L Sun… - BioMed Research …, 2020 - Wiley Online Library
The mechanical properties of cells are closely related to their physiological functions and
states. Analyzing and measuring these properties are beneficial to understanding cell …

[HTML][HTML] Characterization of biomechanical properties of cells through dielectrophoresis-based cell stretching and actin cytoskeleton modeling

G Bai, Y Li, HK Chu, K Wang, Q Tan, J Xiong… - Biomedical engineering …, 2017 - Springer
Background Cytoskeleton is a highly dynamic network that helps to maintain the rigidity of a
cell, and the mechanical properties of a cell are closely related to many cellular functions …

Microfluidic system for cell mechanics analysis through dielectrophoresis

I Guido, C Xiong, MS Jaeger, C Duschl - Microelectronic engineering, 2012 - Elsevier
The cellular mechanical properties and changes in cell mechanics are of enormous
relevance in many cellular processes and play an important role in the normal or …

Measurement of single-cell deformability using impedance analysis on microfluidic chip

D Kim, E Choi, SS Choi, S Lee, J Park… - Japanese journal of …, 2010 - iopscience.iop.org
In this paper, we propose a microfluidic chip that measures the deformability of single cells
by an impedance measurement method. The proposed chip is designed to differentiate the …

Dielectrophoretic microfluidic chip integrated with liquid metal electrode for red blood cell stretching manipulation

B Zhu, Y Cai, Z Wu, F Niu, H Yang - IEEE Access, 2019 - ieeexplore.ieee.org
Cellular mechanical properties are closely related to cell physiological functions and status,
and their analysis and measurement help understand cell mechanism. In this study, a …

[HTML][HTML] The method to quantify cell elasticity based on the precise measurement of pressure inducing cell deformation in microfluidic channels

Z Chen, TF Yip, Y Zhu, JWK Ho, H Chen - MethodsX, 2021 - Elsevier
The cell elasticity has attracted extensive research interests since it not only provides new
insights into cell biology but also is an emerging mechanical marker for the diagnosis of …

[HTML][HTML] Quantifying deformation and migration properties of U87 glioma cells using dielectrophoretic forces

M Elitas, M Islam, JG Korvink, E Sengul, P Sharbati… - Biosensors, 2022 - mdpi.com
Glioblastoma multiforme is one of the most aggressive malignant primary brain tumors. To
design effective treatment strategies, we need to better understand the behavior of glioma …

[PDF][PDF] Automated measurement of cell mechanical properties using an integrated dielectrophoretic microfluidic device

H Yang, M Zhu, T Chen, F Niu, L Sun, L Cheng - Iscience, 2022 - cell.com
Cell mechanics is closely related to and interacts with cellular functions, which has the
potential to be an effective biomarker to indicate disease onset and progression. Although …