In this study, to increase the blood stability and circulation time of polymeric nanoparticles as
well as to investigate the effects of the structure on therapeutic indexes, 2 types of N-(2 …

This study is intended to develop and evaluate a novel, highly water-soluble polymer drug
conjugate poly (l-γ-glutamyl-l-carbocisteine)-paclitaxel (PGSC-PTX) which can trigger drug …

A novel bio-responsive co-delivery system based on Poly (DEA)-b-Poly (ABMA-co-
OEGMA)(PDPAO, prepared by reversible addition-fragmentation chain transfer (RAFT) …

Tumor multidrug resistance (MDR) is one of the main reasons for the failure of clinical
chemotherapy. Here, a bio-responsive anti-drug-resistant polymer micelle that can respond …

The majority of anti-cancer drugs show poor water solubility and produce adverse effects in
healthy tissue. The combination of polymer technology and targeted drug delivery system …

Two antineoplastic agents, Imatinib (IM) and 5-Fluorouracil (FU) were conjugated by
hydrolysable linkers through an amide bond and entrapped in polymeric Human Serum …

Deep eutectic solvents (DESs) are promising biocompatible solvents that have many
applications in biomedical research including drug delivery. In this study, nanomicelles were …

Single-drug therapy for cancer is greatly hampered by its non-specific delivery to the target
tissue, limited efficacies, poor tolerability, and resistance profiles. In order to overcome these …

Purpose Polymeric micelles are attractive nanocarriers for tumor-targeted delivery of
paclitaxel (PTX). High antitumor efficacy and low toxicity require that PTX mainly …

Polymeric nanoparticles have shown great promise as attractive vehicles for drug delivery.
In this study, we designed, prepared and characterized biodegradable amphiphilic triblock …