The aim of the current study was to establish the interplay between blood flow patterns
within a large cerebral artery and a downstream microvascular segment under conditions of …

The ability to maintain adequate cerebral blood flow and oxygenation determines tolerance
to central hypovolemia. We tested the hypothesis that acute hypoxemia during simulated …

Purpose Previous work indicates that dynamic cerebral blood flow (CBF) regulation is
impaired during hypercapnia; however, less is known about the impact of resting …

Background and Purpose—To determine how cerebral blood flow (CBF), total and
microvascular cerebral blood volume (CBV), and blood oxygenation level–dependent …

Lower body negative pressure (LBNP) is often used to simulate blood loss in humans. It is
unknown if cerebral blood flow responses to actual blood loss are analogous to simulated …

Lower body positive pressure (LBPP) has been used in the treatment of haemorrhagic shock
and in offsetting g‐force induced fluid shifts. However, the middle cerebral artery blood flow …

We examined the impact of progressive hypotension with and without hypocapnia on
regional extracranial cerebral blood flow (CBF) and intracranial velocities. Participants …

Purpose Cerebral blood flow (CBF) needs to be precisely controlled to maintain brain
functions. While previously believed to be autoregulated and near constant over a wide …

Background This study evaluated the effects of stroke on regulation of cerebral blood flow in
response to fluctuations in systemic blood pressure (BP). The autoregulatory dynamics are …

Cerebral metabolism is critically dependent on the regulation of cerebral blood flow (CBF),
so it would be expected that vascular mechanisms that play a critical role in CBF regulation …