Evaluation of adenoviral vascular endothelial growth factor-activated chitosan/hydroxyapatite scaffold for engineering vascularized bone tissue using human …

A Koç, G Finkenzeller, AE Elçin… - Journal of …, 2014 - journals.sagepub.com
Bone tissue is dependent on an efficient blood supply to ensure delivery of nutrients and
oxygen. One method to acquire a vascular-engineered bone tissue could be the use of an …

Highly porous multiple-cell-laden collagen/hydroxyapatite scaffolds for bone tissue engineering

YW Koo, H Lee, CS Lim, SY Kwon, I Han… - International Journal of …, 2022 - Elsevier
Efficient vascularization within a scaffold is an essential criterion for evaluating the success
of volumetric bone formation. Various strategies using angiogenic growth factors and cell …

Vascularized bone tissue formation induced by fiber‐reinforced scaffolds cultured with osteoblasts and endothelial cells

X Liu, G Zhang, C Hou, H Wang, Y Yang… - BioMed Research …, 2013 - Wiley Online Library
The repair of the damaged bone tissue caused by damage or bone disease was still a
problem. Current strategies including the use of autografts and allografts have the …

[HTML][HTML] VEGF-loaded biomimetic scaffolds: a promising approach to improve angiogenesis and osteogenesis in an ischemic environment

B Li, H Wang, G Zhou, J Zhang, X Su, Z Huang, Q Li… - RSC …, 2017 - pubs.rsc.org
The treatment of bone defects in an ischemic environment is a huge challenge. Improving
angiogenesis, which is regulated by angiogenic growth factors such as vascular endothelial …

Controlled release of vascular endothelial growth factor from spray‐dried alginate microparticles in collagen–hydroxyapatite scaffolds for promoting vascularization …

E Quinlan, A López‐Noriega… - Journal of tissue …, 2017 - Wiley Online Library
A major limitation with current tissue‐engineering approaches is creating functionally
vascularized constructs that can successfully integrate with the host; this often leads to …

Injectable hydrogel delivering bone morphogenetic protein-2, vascular endothelial growth factor, and adipose-derived stem cells for vascularized bone tissue …

T Wang, S Guo, H Zhang, Y Chen, Y Cai - Journal of Drug Delivery Science …, 2020 - Elsevier
We aimed to evaluate the integration of stem cells with injectable microspheres loaded with
growth factors using a chitosan (CS) scaffold to promote healthy bone regeneration. We …

[HTML][HTML] Assessment of the release of vascular endothelial growth factor from 3D-printed poly-ε-caprolactone/hydroxyapatite/calcium sulfate scaffold with enhanced …

CY Chen, CC Chen, CY Wang, AKX Lee, CL Yeh… - Polymers, 2020 - mdpi.com
Vascular endothelial growth factor (VEGF) is one of the most crucial growth factors and an
assistant for the adjustment of bone regeneration. In this study, a 3D scaffold is fabricated …

Bioprinted chitosan and hydroxyapatite micro-channels structures scaffold for vascularization of bone regeneration

Y Liu, S Li, Y Sun, Y Li, C Jiang… - Journal of Biomaterials …, 2017 - ingentaconnect.com
In this work, we presented a new materials composed of hollow chitosan and hydroxyapatite
(CS/HA) fibers were bio-fabricated by combining a coaxial extrusion with a water bath …

Hyaluronic acid oligosaccharides modified mineralized collagen and chitosan with enhanced osteoinductive properties for bone tissue engineering

M Li, W Jia, X Zhang, H Weng, G Gu, Z Chen - Carbohydrate polymers, 2021 - Elsevier
In this study, we prepared a biomimetic hyaluronic acid oligosaccharides (oHAs)-based
composite scaffold to develop a bone tissue-engineered scaffold for stimulating …

[HTML][HTML] Bone tissue engineering scaffolds with HUVECs/hBMSCs cocultured on 3D-printed composite bioactive ceramic scaffolds promoted osteogenesis …

X Liu, N Zhao, H Liang, B Tan, F Huang, H Hu… - Journal of Orthopaedic …, 2022 - Elsevier
Abstract Background/Objective: Tissue engineering involves scaffolds, cells and growth
factors, among which growth factors have limited applications due to potential safety risks …